diethyl 5-anilino-1H-pyrazole-3,4-dicarboxylate

Base Information

Chemical Name:diethyl 5-anilino-1H-pyrazole-3,4-dicarboxylate
CAS No.:142115-59-1
Molecular Formula:C₁₅H₁₇N₃O₄
Molecular Weight:303.318
Hs Code.:
European Community (EC) Number:669-140-3
Mol file:142115-59-1.mol

Synonyms:142115-59-1;Diethyl 5-(phenylamino)-1H-pyrazole-3,4-dicarboxylate;diethyl 5-anilino-1H-pyrazole-3,4-dicarboxylate;AKOS001874460

Suppliers and Price of diethyl 5-anilino-1H-pyrazole-3,4-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of diethyl 5-anilino-1H-pyrazole-3,4-dicarboxylate

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:303.12190603
Heavy Atom Count:22
Complexity:385

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=C(NN=C1NC2=CC=CC=C2)C(=O)OCC

Technology Process of diethyl 5-anilino-1H-pyrazole-3,4-dicarboxylate

There total 3 articles about diethyl 5-anilino-1H-pyrazole-3,4-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 5351-69-9
4-Phenyl-3-thiosemicarbazide

: 34034-87-2
diethyl 3-chloro-2-oxosuccinate

: 142115-59-1
5-Phenylamino-1H-pyrazole-3,4-dicarboxylic acid diethyl ester

Guidance literature:: In ethanol; a) RT, 8 h, b) reflux, 2 h;
DOI:10.1135/cccc19920656

Reference yield:

: 103-72-0
phenyl isothiocyanate

: 142115-59-1
5-Phenylamino-1H-pyrazole-3,4-dicarboxylic acid diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: aq. sodium chloroacetate, hydrazine / ethanol / 4 h / Ambient temperature

2: 49 percent / ethanol / a) RT, 8 h, b) reflux, 2 h

With sodium monochloroacetic acid; hydrazine; In ethanol;
DOI:10.1135/cccc19920656

Reference yield:

: 62-53-3
aniline

: 142115-59-1
5-Phenylamino-1H-pyrazole-3,4-dicarboxylic acid diethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: aq. ammonia / ethanol / 4 h / Ambient temperature

2: aq. sodium chloroacetate, hydrazine / ethanol / 4 h / Ambient temperature

3: 49 percent / ethanol / a) RT, 8 h, b) reflux, 2 h

With ammonium hydroxide; sodium monochloroacetic acid; hydrazine; In ethanol;
DOI:10.1135/cccc19920656