1H-INDOLE-1,5-DICARBOXYLIC ACID,2,3-DIHYDRO-,1-(PHENYLMETHYL)ESTER

Base Information

Chemical Name:1H-INDOLE-1,5-DICARBOXYLIC ACID,2,3-DIHYDRO-,1-(PHENYLMETHYL)ESTER
CAS No.:142165-63-7
Molecular Formula:C17H15NO4
Molecular Weight:297.30500
Hs Code.:
Mol file:142165-63-7.mol

Synonyms:2,3-Dihydro-indole-1,5-dicarboxylic acid 1-benzyl ester;1H-INDOLE-1,5-DICARBOXYLIC ACID,2,3-DIHYDRO-,1-(PHENYLMETHYL)ESTER;

Suppliers and Price of 1H-INDOLE-1,5-DICARBOXYLIC ACID,2,3-DIHYDRO-,1-(PHENYLMETHYL)ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
1H-INDOLE-1,5-DICARBOXYLICACID,2,3-DIHYDRO-,1-(PHENYLMETHYL)ESTER 95
1g
$ 1233.00

American Custom Chemicals Corporation
1H-INDOLE-1,5-DICARBOXYLIC ACID,2,3-DIHYDRO-,1-(PHENYLMETHYL)ESTER 95.00%
5MG
$ 499.82

Total 3 raw suppliers

Chemical Property of 1H-INDOLE-1,5-DICARBOXYLIC ACID,2,3-DIHYDRO-,1-(PHENYLMETHYL)ESTER

Chemical Property:

Boiling Point:509.4±50.0 °C(Predicted)
PKA:4.45±0.20(Predicted)
PSA：66.84000
Density:1.348±0.06 g/cm3(Predicted)
LogP:3.14910

Purity/Quality:

99% ^*data from raw suppliers

1H-INDOLE-1,5-DICARBOXYLICACID,2,3-DIHYDRO-,1-(PHENYLMETHYL)ESTER 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-INDOLE-1,5-DICARBOXYLIC ACID,2,3-DIHYDRO-,1-(PHENYLMETHYL)ESTER

There total 1 articles about 1H-INDOLE-1,5-DICARBOXYLIC ACID,2,3-DIHYDRO-,1-(PHENYLMETHYL)ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 15861-30-0
2,3-dihydro-1H-indole-5-formic acid

: 501-53-1,94274-21-2
benzyl chloroformate

: 142165-63-7
1-carbobenzoxy-5-carboxyindoline

Guidance literature:: With sodium hydroxide; In diethyl ether; water; Ambient temperature;
DOI:10.1248/cpb.44.1332

Reference yield:

: 5722-17-8
dimethyl (RS)-2-aminohexanedioate hydrochloride

: 142165-63-7
1-carbobenzoxy-5-carboxyindoline

: dimethyl N-(1-carbobenzoxyindolin-5-carbonyl)-L-α-aminoadipate

Guidance literature:: With potassium carbonate; N-methyl-acetamide; In thionyl chloride; dichloromethane;

Reference yield:

: 142165-63-7
1-carbobenzoxy-5-carboxyindoline

: 142165-84-2
(S)-2-[(2,3-Dihydro-1H-indole-5-carbonyl)-amino]-4-phenylcarbamoyl-butyric acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂ / dimethylformamide / 1 h

2: aq. K₂CO₃ / CH₂Cl₂ / 10 h / Ambient temperature

3: H₂ / 5percent Pd/C / methanol / Ambient temperature

With thionyl chloride; hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.45.1146