Propanoic acid, 3-(triphenylgermyl)-

Base Information

• Chemical Name: Propanoic acid, 3-(triphenylgermyl)-
• CAS No.: 142208-35-3
• Molecular Formula: C21H20GeO2
• Molecular Weight: 376.979
• DSSTox Substance ID: DTXSID80413351
• Nikkaji Number: J1.467.837I
• Wikidata: Q82221373
• Mol file: 142208-35-3.mol

Synonyms:Propanoic acid, 3-(triphenylgermyl)-;142208-35-3;DTXSID80413351

Chemical Property of Propanoic acid, 3-(triphenylgermyl)-

Chemical Property:

• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 378.0675076
• Heavy Atom Count: 24
• Complexity: 345

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)[Ge](CCC(=O)O)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Propanoic acid, 3-(triphenylgermyl)-

There total 1 articles about Propanoic acid, 3-(triphenylgermyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.7%

3-(trichlorogermyl)propionic acid (15961-23-6) + phenylmagnesium bromide (100-58-3) → β-(triphenylgermyl)propanoic acid (142208-35-3)

Guidance literature:

In tetrahydrofuran;

DOI:10.1016/j.jorganchem.2009.05.003

Reference yield: 94.0%

β-(triphenylgermyl)propanoic acid (142208-35-3) + [(S(CH2C6H4)2)BiCl] (1186337-98-3) → [(S(CH2C6H4)2)Bi(OC(O)CH2CH2Ge(C6H5)3)] (1188272-36-7)

Guidance literature:

With NaOH; In tetrahydrofuran; water; (N2); std. Schlenk technique; mixt. of Bi compd., soln. of Ge compd. in THF and aq. soln. of NaOH was refluxed for 10 h; THF removed (vac.); dissolved in CH2Cl2; washed (H2O); org. layer septd.; dried (MgSO4); evapd. (vac.); elem. anal.;

DOI:10.1016/j.jorganchem.2009.05.003

Reference yield: 94.0%

β-(triphenylgermyl)propanoic acid (142208-35-3) + [(C6H11N(CH2C6H4)2)BiCl] (1186324-27-5) → [(C6H11N(CH2C6H4)2)Bi(OC(O)CH2CH2Ge(C6H5)3)] (1188272-39-0)

Guidance literature:

With NaOH; In tetrahydrofuran; water; (N2); std. Schlenk technique; mixt. of Bi compd., soln. of Ge compd. in THF and aq. soln. of NaOH was refluxed for 10 h; THF removed (vac.); dissolved in CH2Cl2; washed (H2O); org. layer septd.; dried (MgSO4); evapd. (vac.); elem. anal.;

DOI:10.1016/j.jorganchem.2009.05.003

upstream raw materials:

3-(trichlorogermyl)propionic acid

phenylmagnesium bromide

Downstream raw materials:

(C₆H₅)3GeCH₂CH₂COOSn(CH₂C(CH₃)2C₆H₅)3

(C₆H₅)3Sb(OCOCH₂CH₂Ge(C₆H₅)3)2

tetraphenylantimony(V) triphenylgermanylpropionate

(C₆H₅)3GeCH₂CH₂C(O)N(CH₂C₆H₅)(CHC₆H₄Cl)(P(O)(OCH₃)2)