1,2,3,4-Tetrahydro-1-(p-fluorophenyl)-6-methoxy-2-phenyl-1-naphthol

Base Information

Chemical Name:1,2,3,4-Tetrahydro-1-(p-fluorophenyl)-6-methoxy-2-phenyl-1-naphthol
CAS No.:4310-62-7
Molecular Formula:C₂₃H₂₁FO₂
Molecular Weight:348.417
Hs Code.:
DSSTox Substance ID:DTXSID40962895
Mol file:4310-62-7.mol

Synonyms:BRN 2016145;1,2,3,4-Tetrahydro-1-(p-fluorophenyl)-6-methoxy-2-phenyl-1-naphthol;1-(p-Fluorophenyl)-6-methoxy-2-phenyl-1,2,3,4-tetrahydro-1-naphthol;1-NAPHTHOL, 1,2,3,4-TETRAHYDRO-1-(p-FLUOROPHENYL)-6-METHOXY-2-PHENYL-;4310-62-7;C23H21FO2;DTXSID40962895;C23-H21-F-O2;LS-95465;1-(4-Fluorophenyl)-6-methoxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-ol

Suppliers and Price of 1,2,3,4-Tetrahydro-1-(p-fluorophenyl)-6-methoxy-2-phenyl-1-naphthol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1,2,3,4-Tetrahydro-1-(p-fluorophenyl)-6-methoxy-2-phenyl-1-naphthol

Chemical Property:

Vapor Pressure:1.25E-09mmHg at 25°C
Boiling Point:469.8°Cat760mmHg
Flash Point:206.6°C
Density:1.208g/cm³
XLogP3:4.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:348.15255807
Heavy Atom Count:26
Complexity:455

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(C(CC2)C3=CC=CC=C3)(C4=CC=C(C=C4)F)O

Technology Process of 1,2,3,4-Tetrahydro-1-(p-fluorophenyl)-6-methoxy-2-phenyl-1-naphthol

There total 6 articles about 1,2,3,4-Tetrahydro-1-(p-fluorophenyl)-6-methoxy-2-phenyl-1-naphthol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-52-7
benzaldehyde

: 4310-62-7
1-(4-Fluoro-phenyl)-6-methoxy-2-phenyl-1,2,3,4-tetrahydro-naphthalen-1-ol

Guidance literature:: Multi-step reaction with 5 steps

1: (i) aq. NaOH, EtOH, (ii) /BRN= 471223/

2: AcOH / aq. ethanol

3: aq. H₂SO₄

4: (i) Zn-Hg, aq. HCl, (ii) HF

5: (i) Mg, Et₂O, THF, (ii) /BRN= 1472433/

With sulfuric acid; acetic acid; In ethanol;
DOI:10.1021/jm00320a002

Reference yield:

: 586-37-8
1-(3-Methoxyphenyl)ethanone

: 4310-62-7
1-(4-Fluoro-phenyl)-6-methoxy-2-phenyl-1,2,3,4-tetrahydro-naphthalen-1-ol

Guidance literature:: Multi-step reaction with 5 steps

1: (i) aq. NaOH, EtOH, (ii) /BRN= 471223/

2: AcOH / aq. ethanol

3: aq. H₂SO₄

4: (i) Zn-Hg, aq. HCl, (ii) HF

5: (i) Mg, Et₂O, THF, (ii) /BRN= 1472433/

With sulfuric acid; acetic acid; In ethanol;
DOI:10.1021/jm00320a002

Reference yield:

: 1729-33-5
2-Phenyl-4-(3-methoxyphenyl)-4-ketobutyronitril

: 4310-62-7
1-(4-Fluoro-phenyl)-6-methoxy-2-phenyl-1,2,3,4-tetrahydro-naphthalen-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1: aq. H₂SO₄

2: (i) Zn-Hg, aq. HCl, (ii) HF

3: (i) Mg, Et₂O, THF, (ii) /BRN= 1472433/

With sulfuric acid;
DOI:10.1021/jm00320a002