5-Chloro-4,6-dimethylpyrimidin-2-amine

Base Information

Chemical Name:5-Chloro-4,6-dimethylpyrimidin-2-amine
CAS No.:7749-61-3
Molecular Formula:C6H8ClN3
Molecular Weight:157.6008
Hs Code.:
NSC Number:405571
DSSTox Substance ID:DTXSID60324052
Nikkaji Number:J100.861G
Wikidata:Q82083436
Mol file:7749-61-3.mol

Synonyms:5-chloro-4,6-dimethylpyrimidin-2-amine;7749-61-3;2-Pyrimidinamine, 5-chloro-4,6-dimethyl-;2-AMINO-5-CHLORO-4,6-DIMETHYLPYRIMIDINE;NSC 405571;Pyrimidine, 2-amino-5-chloro-4,6-dimethyl-;NSC405571;SCHEMBL11461473;DTXSID60324052;AKOS006311192;AB54992;NSC-405571;2-amino-4,6-dimethyl-5-chloropyrimidine;5-Chloro-4,6-dimethyl-2-pyrimidinamine #;FT-0736673

Suppliers and Price of 5-Chloro-4,6-dimethylpyrimidin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-CHLORO-4,6-DIMETHYLPYRIMIDIN-2-AMINE 95.00%
5MG
$ 505.51

Total 7 raw suppliers

Chemical Property of 5-Chloro-4,6-dimethylpyrimidin-2-amine

Chemical Property:

Vapor Pressure:0.000172mmHg at 25°C
Boiling Point:329.9°Cat760mmHg
Flash Point:153.3°C
PSA：51.80000
Density:1.284g/cm³
LogP:1.91020
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:157.0406750
Heavy Atom Count:10
Complexity:108

Purity/Quality:

98%min ^*data from raw suppliers

5-CHLORO-4,6-DIMETHYLPYRIMIDIN-2-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=NC(=N1)N)C)Cl

Technology Process of 5-Chloro-4,6-dimethylpyrimidin-2-amine

There total 2 articles about 5-Chloro-4,6-dimethylpyrimidin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 767-15-7,184433-59-8
2-Amino-4,6-dimethylpyrimidine

: 7749-61-3
2-amino-5-chloro-4,6-dimethylpyrimidine

Guidance literature:: With water; chlorine; calcium carbonate;
DOI:10.1021/ja01212a070

Reference yield:

: 7749-61-3
2-amino-5-chloro-4,6-dimethylpyrimidine

Guidance literature:: 2-Amino-4,6-dimethyl-pyrimidin, N-Chlorsuccinimid/sd.CHCl3;
DOI:10.1016/S0040-4020(01)99029-5

Reference yield:

: 7749-61-3
2-amino-5-chloro-4,6-dimethylpyrimidine

: (1R,2R)-2-(5-Chloro-4,6-dimethyl-pyrimidin-2-ylamino)-1,2-diphenyl-ethanol

Guidance literature:: Multi-step reaction with 3 steps

1: t-BuOCl / ethanol / 20 °C

2: NaOH / H₂O / 0 °C

3: 1,4-bis(dihydroguininyl)phthalazine; H₂O / K₂OsO₂(OH)4 / 20 °C

With (3a,9R,3'''a,4'"b,9'"R)-9,9'-[1,4-phthalazinediylbis(oxy)]bis[6'-(methyloxy)-10,11-dihydrocinchonan]; sodium hydroxide; tert-butylhypochlorite; water; potassium dioxotetrahydroxoosmate(VI); In ethanol; water; 1: Chlorination / 2: Metallation / 3: Addition;
DOI:10.1002/(SICI)1521-3773(19990419)38:8<1080::AID-ANIE1080>3.0.CO;2-D