1-Tert-butoxy-4-fluoro-2-nitrobenzene

Base Information

Chemical Name:1-Tert-butoxy-4-fluoro-2-nitrobenzene
CAS No.:142596-59-6
Molecular Formula:C10H12FNO3
Molecular Weight:213.209
Hs Code.:
DSSTox Substance ID:DTXSID40470501
Nikkaji Number:J2.239.062G
Wikidata:Q82298613

Synonyms:1-tert-butoxy-4-fluoro-2-nitrobenzene;142596-59-6;Benzene, 1-(1,1-dimethylethoxy)-4-fluoro-2-nitro-;SCHEMBL1135919;DTXSID40470501;CJGDTWBHCUOVFN-UHFFFAOYSA-N;4-fluoro-1-[(2-methylpropan-2-yl)oxy]-2-nitrobenzene

Suppliers and Price of 1-Tert-butoxy-4-fluoro-2-nitrobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Tert-butoxy-4-fluoro-2-nitrobenzene

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:213.08012141
Heavy Atom Count:15
Complexity:234

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC1=C(C=C(C=C1)F)[N+](=O)[O-]

Technology Process of 1-Tert-butoxy-4-fluoro-2-nitrobenzene

There total 1 articles about 1-Tert-butoxy-4-fluoro-2-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 364-74-9
1,4-difluoro-2-nitrobenzene

: 865-47-4
potassium tert-butylate

: 142596-59-6
1-tert-butoxy-4-fluoro-2-nitrobenzene

Guidance literature:: In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1021/ol0518840

Reference yield: 96.0%

: 142596-59-6
1-tert-butoxy-4-fluoro-2-nitrobenzene

: 862594-16-9
2-tert-butoxy-5-fluoroaniline

Guidance literature:: With hydrogen; platinum(IV) oxide; In methanol; at 20 ℃; for 18h; under 760 Torr;
DOI:10.1021/ol0518840

Reference yield:

: 142596-59-6
1-tert-butoxy-4-fluoro-2-nitrobenzene

: 663925-82-4
O-isopropyl 2-tert-butoxy-5-fluorophenylthiocarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / H₂ / PtO₂ / methanol / 18 h / 20 °C / 760 Torr

2: 83 percent / EtOCOCl; Et₃N / toluene; CHCl₃ / 20 °C

3: 80 percent / Et₃N / Heating

With hydrogen; chloroformic acid ethyl ester; triethylamine; platinum(IV) oxide; In methanol; chloroform; toluene;
DOI:10.1021/ol0518840