7-(Benzyloxy)-2-naphthol

Base Information

• Chemical Name: 7-(Benzyloxy)-2-naphthol
• CAS No.: 118495-07-1
• Molecular Formula: C17H14 O2
• Molecular Weight: 250.297
• Hs Code.: 2909499000
• DSSTox Substance ID: DTXSID10377154
• Nikkaji Number: J1.253.335G
• Wikidata: Q82166245
• Mol file: 118495-07-1.mol

Synonyms:7-(benzyloxy)-2-naphthol;118495-07-1;7-(benzyloxy)naphthalen-2-ol;7-phenylmethoxynaphthalen-2-ol;2-benzyloxynaphth-7-ol;7-benzyloxy-2-naphthol;7-benzyloxynaphthalen-2-ol;7-benzyloxy-naphthalen-2-ol;Oprea1_598295;7-benzyloxy-naphthalene-2-ol;7-phenylmethoxy-2-naphthalenol;SCHEMBL3818205;2-benzyloxy-7-hydroxynaphthalene;DTXSID10377154;UNBCQJKOYUSQAW-UHFFFAOYSA-N;2-PROPYL-1-INDANONE,98;MFCD03425751;AKOS005070157;CS-0367444;FT-0642897;3T-0008;A804039;A804139

Chemical Property of 7-(Benzyloxy)-2-naphthol

Chemical Property:

• Vapor Pressure: 1.68E-08mmHg at 25°C
• Melting Point: 151-152°C
• Boiling Point: 444.1°Cat760mmHg
• Flash Point: 279.2°C
• PSA: 29.46000
• Density: 1.21g/cm³
• LogP: 4.12440
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 250.099379685
• Heavy Atom Count: 19
• Complexity: 272

Purity/Quality:

97% ^*data from raw suppliers

7-(Benzyloxy)-2-naphthol >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=CC3=C(C=CC(=C3)O)C=C2

Technology Process of 7-(Benzyloxy)-2-naphthol

There total 7 articles about 7-(Benzyloxy)-2-naphthol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

2,7-Dihydroxynaphthalene (582-17-2) + benzyl chloride (100-44-7) → 7-(benzyloxy)-2-naphthol (118495-07-1)

Guidance literature:

With potassium carbonate; In butanone; for 25h; Heating;

DOI:10.1039/b419479a

Reference yield: 39.0%

2,7-Dihydroxynaphthalene (582-17-2) + benzyl bromide (100-39-0) → 7-(benzyloxy)-2-naphthol (118495-07-1)

Guidance literature:

for 4h; Heating;

DOI:10.1248/cpb.50.272

Reference yield:

2-acetoxy-7-benzyloxynaphthalene (1257230-84-4) → 7-(benzyloxy)-2-naphthol (118495-07-1)

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; water; at 25 ℃; for 24h; Inert atmosphere;

DOI:10.1002/anie.202004671

upstream raw materials:

2,7-Dihydroxynaphthalene

benzyl chloride

benzyl bromide

2-acetoxy-7-benzyloxynaphthalene

Downstream raw materials:

(R)-7,7-bis(benzyloxy)-2,2'-dihydroxy-1,1'-binaphthyl

(S)‐7,7′‐bis(benzyloxy)‐[1,1′‐binaphthalene]‐2,2′‐diol

()-7,7'-bis-benzyloxy-[1,1']-binaphthalene-2,2'-diol

ethyl 2-(((7-benzyloxy)naphthalene)oxy)acetate