2-[5-Chloro-2-(4-fluorophenyl)-1H-indol-3-YL]-N,N-dihexylacetamide

Base Information

Chemical Name:2-[5-Chloro-2-(4-fluorophenyl)-1H-indol-3-YL]-N,N-dihexylacetamide
CAS No.:142720-25-0
Molecular Formula:C₂₈H₃₆ClFN₂O
Molecular Weight:471.058
Hs Code.:
DSSTox Substance ID:DTXSID30435528
Wikidata:Q82250541
ChEMBL ID:CHEMBL98613

Synonyms:CHEMBL98613;142720-25-0;2-[5-CHLORO-2-(4-FLUOROPHENYL)-1H-INDOL-3-YL]-N,N-DIHEXYLACETAMIDE;DTXSID30435528;BDBM50045892;2-[5-Chloro-2-(4-fluoro-phenyl)-1H-indol-3-yl]-N,N-dihexyl-acetamide

Suppliers and Price of 2-[5-Chloro-2-(4-fluorophenyl)-1H-indol-3-YL]-N,N-dihexylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-[5-Chloro-2-(4-fluorophenyl)-1H-indol-3-YL]-N,N-dihexylacetamide

Chemical Property:

XLogP3:8.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:13
Exact Mass:470.2500196
Heavy Atom Count:33
Complexity:556

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=C1C=C(C=C2)Cl)C3=CC=C(C=C3)F

Technology Process of 2-[5-Chloro-2-(4-fluorophenyl)-1H-indol-3-YL]-N,N-dihexylacetamide

There total 5 articles about 2-[5-Chloro-2-(4-fluorophenyl)-1H-indol-3-YL]-N,N-dihexylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-[(4-Chloro-phenyl)-hydrazono]-4-(4-fluoro-phenyl)-N,N-dihexyl-butyramide

: 142720-25-0
FGIN 1-45

Guidance literature:: With zinc(II) chloride; at 170 ℃; for 0.0833333h; Yield given;
DOI:10.1021/jm00072a010

Reference yield:

: 366-77-8
4-(4-fluorophenyl)-4-oxopropionic acid

: 142720-25-0
FGIN 1-45

Guidance literature:: Multi-step reaction with 4 steps

1: Et₃N / tetrahydrofuran / 0.5 h / -40 deg C to -20 deg C

2: Ambient temperature

3: 0.5 h / 100 °C

4: ZnCl₂ / 0.08 h / 170 °C

With triethylamine; zinc(II) chloride; In tetrahydrofuran;

Reference yield:

: 143-16-8
dihexylamine

: 142720-25-0
FGIN 1-45

Guidance literature:: Multi-step reaction with 3 steps

1: Ambient temperature

2: 0.5 h / 100 °C

3: ZnCl₂ / 0.08 h / 170 °C

With zinc(II) chloride;