Glycylphenylalaninamide acetate(1:1)

Base Information

• Chemical Name: Glycylphenylalaninamide acetate(1:1)
• CAS No.: 13467-26-0
• Molecular Formula: C13H19N3O4
• Molecular Weight: 257.72
• Hs Code.: 2924299090
• NSC Number: 89623
• DSSTox Substance ID: DTXSID10293446
• Mol file: 13467-26-0.mol

Synonyms:glycylphenylalaninamide acetate(1:1);13467-26-0;acetic acid;2-[(2-aminoacetyl)amino]-3-phenylpropanamide;(S)-2-(2-Aminoacetamido)-3-phenylPropanamide acetate;glycyl-l-phenylalaninamide;NSC89623;Gly-Phe-NH2.AcOH;H-GLY-PHE-NH2HCL;DTXSID10293446;NSC-89623

Chemical Property of Glycylphenylalaninamide acetate(1:1)

Chemical Property:

• Vapor Pressure: 9.41E-12mmHg at 25°C
• Boiling Point: 540.6°C at 760 mmHg
• Flash Point: 280.7°C
• PSA: 135.51000
• LogP: 1.04030
• Storage Temp.: -15°C
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 281.13755610
• Heavy Atom Count: 20
• Complexity: 281

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)O.C1=CC=C(C=C1)CC(C(=O)N)NC(=O)CN

Technology Process of Glycylphenylalaninamide acetate(1:1)

There total 3 articles about Glycylphenylalaninamide acetate(1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

benzyloxycarbonyl-glycyl-L-phenylalanine amide (5513-69-9) + acetic acid (64-19-7,77671-22-8) → glycyl-L-phenylalanine amide acetate (13467-26-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; at 60 ℃; for 1.5h;

DOI:10.1021/jm00387a027

Reference yield:

benzyloxycarbonyl-glycyl-L-phenylalanine amide (5513-69-9) → glycyl-L-phenylalanine amide acetate (13467-26-0)

Guidance literature:

With methanol; palladium; acetic acid; Hydrogenation;

Reference yield:

CbzGly-L-PheOEt (3956-78-3) → glycyl-L-phenylalanine amide acetate (13467-26-0)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; ammonia

2: palladium; acetic acid; methanol / Hydrogenation

With methanol; ammonia; palladium; acetic acid;

upstream raw materials:

benzyloxycarbonyl-glycyl-L-phenylalanine amide

acetic acid

CbzGly-L-PheOEt

Downstream raw materials:

(tert-butyloxycarbonyl)-L-tryptophylglycyl-L-phenylalanine amide