Xylometazoline hydrochloride

Base Information

• Chemical Name: Xylometazoline hydrochloride
• CAS No.: 1218-35-5
• Deprecated CAS: 28096-10-8
• Molecular Formula: C16H25ClN2
• Molecular Weight: 280.841
• Hs Code.: 29332900
• European Community (EC) Number: 214-936-4
• NSC Number: 757378
• UNII: X5S84033NZ
• DSSTox Substance ID: DTXSID3045223
• Wikidata: Q27293585
• NCI Thesaurus Code: C87583
• RXCUI: 54220
• ChEMBL ID: CHEMBL1256400
• Mol file: 1218-35-5.mol

Synonyms:2-(4'-tert-butyl-2',6'-dimethylphenylmethyl)imidazoline;Amidrin;Balkis;Chlorohist-LA;Decongest;espa-rhin;Gelonasal;Idasal;Idril N;Imidin;Nasan;Nasengel AL;NasenGel ratiopharm;Nasenspray AL;NasenSpray ratiopharm;Nasentropfen AL;NasenTropfen ratiopharm;Novorin;Otradrops;Otraspray;Otriven;Otrivin;Otrivin Mentol;Rapako;schnupfen endrine;Snup;stas;xylometazoline;xylometazoline hydrochloride;xylometazoline monohydrochloride

Chemical Property of Xylometazoline hydrochloride

Chemical Property:

• Appearance/Colour: white to off-white crystalline powder
• Vapor Pressure: 4.56E-06mmHg at 25°C
• Melting Point: 131-133 °C
• Boiling Point: 394.2 °C at 760 mmHg
• Flash Point: 192.2 °C
• PSA: 24.39000
• Density: ==
• LogP: 3.71150
• Storage Temp.: 2-8°C
• Solubility.: Freely soluble in water, in ethanol (96 per cent) and in methanol.
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 280.1706265
• Heavy Atom Count: 19
• Complexity: 302

Purity/Quality:

99% ^*data from raw suppliers

Xylometazoline Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1CC2=NCCN2)C)C(C)(C)C.Cl
• Recent ClinicalTrials: Nasal Prep for Nasendoscopy in Children
• Recent EU Clinical Trials: Multicentre, randomized, double-blind, parallel design clinical trial of efficacy, safety and tolerability of Xylometazoline + Sodium Hyaluronate nasal spray, compared to Xylometazoline, Sodium Hyaluronate and Placebo nasal sprays, in adolescent and adult patients with acute viral rhinosinusitis
• Uses: Xylometazoline hydrochloride may be used as a reference standard in determining the xylometazoline hydrochloride content in samples of nasal drops using high performance liquid chromatography (HPLC). Xylometazoline hydrochloride is used as a nasal decongestant. anthelmintic