Allopumiliotoxin 267a

Base Information

Chemical Name:Allopumiliotoxin 267a
CAS No.:73376-38-2
Molecular Formula:C₁₆H₂₉NO₂
Molecular Weight:267.412
Hs Code.:
NSC Number:699383
UNII:TEP57TLJ38
DSSTox Substance ID:DTXSID301027204
Nikkaji Number:J464.939G
Wikipedia:Allopumiliotoxin_267A
Wikidata:Q530596
ChEMBL ID:CHEMBL2002405

Synonyms:allo-pumiliotoxin 267A;allopumiliotoxin 267A

Suppliers and Price of Allopumiliotoxin 267a

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Allopumiliotoxin 267a

Chemical Property:

Vapor Pressure:1.89E-07mmHg at 25°C
Boiling Point:383.2°C at 760 mmHg
Flash Point:169.5°C
PSA：43.70000
Density:1.06g/cm³
LogP:2.26690
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:267.219829168
Heavy Atom Count:19
Complexity:342

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC(C)C=C1CN2CCCC2C(C1O)(C)O
Isomeric SMILES:CCCC[C@@H](C)/C=C/1\CN2CCC[C@H]2[C@@]([C@@H]1O)(C)O

Technology Process of Allopumiliotoxin 267a

There total 53 articles about Allopumiliotoxin 267a which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 91550-12-8
(8R,8_αS)-8-hydroxy-8-methyl-6-((Z)-2(R)-methyl-hexylidene)octahydroindolizin-7-one

: 73376-38-2
(+)-allopumiliotoxin 267A

Guidance literature:: With tetramethylammonium triacetoxyborohydride; In acetic acid; acetone;
DOI:10.1021/ol0069709

Reference yield: 90.0%

: 153108-88-4
(7S,8R,8aS)-8-(benzyloxy)-7-hydroxy-8-methyl-6-(E)-<(2R)-2-methylpentylidene>octahydroindolizidine

: 73376-38-2
(+)-allopumiliotoxin 267A

Guidance literature:: With ammonia; lithium; In tetrahydrofuran; at -78 ℃; for 0.5h;

Reference yield:

: 132151-88-3
R-(-)-2-methylhexanal

: 73376-38-2
(+)-allopumiliotoxin 267A

Guidance literature:: Multi-step reaction with 2 steps

1.1: trityllithium / tetrahydrofuran

1.2: tetrahydrofuran

1.3: 51 percent / DBU; DMAP; TFAA / tetrahydrofuran

2.1: 95 percent / Me₄NBH(OAc)3 / acetone; acetic acid

With trityllithium; tetramethylammonium triacetoxyborohydride; In tetrahydrofuran; acetic acid; acetone;
DOI:10.1021/ol0069709