1-(N-benzyloxycarbonylpyrrolidin-2-yl)-3-hydroxypropene

Base Information

• Chemical Name: 1-(N-benzyloxycarbonylpyrrolidin-2-yl)-3-hydroxypropene
• CAS No.: 143321-94-2
• Molecular Formula: C15H19NO3
• Molecular Weight: 261.321
• DSSTox Substance ID: DTXSID701166901
• Mol file: 143321-94-2.mol

Synonyms:benzyl 2-(3-hydroxyprop-1-en-1-yl)pyrrolidine-1-carboxylate;XRVPHGWCSXRKAY-UHFFFAOYSA-N;DTXSID701166901;1-(N-benzyloxycarbonylpyrrolidin-2-yl)-3-hydroxypropene;(+/-)-3-(N-benzyloxycarbonylpyrrolidin-2-yl)-2-propen-1-ol;Phenylmethyl 2-(3-hydroxy-1-propen-1-yl)-1-pyrrolidinecarboxylate

Chemical Property of 1-(N-benzyloxycarbonylpyrrolidin-2-yl)-3-hydroxypropene

Chemical Property:

• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 261.13649347
• Heavy Atom Count: 19
• Complexity: 311

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C=CCO

Technology Process of 1-(N-benzyloxycarbonylpyrrolidin-2-yl)-3-hydroxypropene

There total 1 articles about 1-(N-benzyloxycarbonylpyrrolidin-2-yl)-3-hydroxypropene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+/-)-3-(N-benzyloxycarbonylpyrrolidin-2-yl)acrylic acid ethyl ester → (+/-)-3-(N-benzyloxycarbonylpyrrolidin-2-yl)-2-propen-1-ol (143321-94-2)

Guidance literature:

(+/-)-3-(N-benzyloxycarbonylpyrrolidin-2-yl)acrylic acid ethyl ester; With diisobutylaluminium hydride; In dichloromethane; toluene; at -70 ℃; for 1h;

With hydrogenchloride; In dichloromethane; water; toluene;

Reference yield:

(+/-)-3-(N-benzyloxycarbonylpyrrolidin-2-yl)-2-propen-1-ol (143321-94-2) → (+/-)-3-(2-pyrrolidinyl)-1-propanol (7699-50-5)

Guidance literature:

With hydrogen; 5%-palladium/activated carbon; In ethanol; at 35 ℃; for 8h; under 760.051 Torr;

Downstream raw materials:

(+/-)-3-(2-pyrrolidinyl)-1-propanol