7699-50-5Relevant academic research and scientific papers
Catalyst-Controlled Diastereoselective Synthesis of Cyclic Amines via C-H Functionalization
Munnuri, Sailu,Adebesin, Adeniyi Michael,Paudyal, Mahesh P.,Yousufuddin, Muhammed,Dalipe, Alfonso,Falck, John R.
supporting information, p. 18288 - 18294 (2017/12/27)
Reliable regio- and stereochemical techniques applicable to nonactivated aliphatic systems remain largely elusive due to the challenges of discriminating between multiple, relatively strong sp3 C-H bonds whose chemical behavior often differ onl
HETEROCYCLIC COMPOUND DERIVATIVES AND MEDICINES
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Page 23, (2010/02/05)
The present invention provides a compound which is useful as a PGI2 receptor agonist, and a pharmaceutical composition. The present invention is directed to a pharmaceutical composition comprising a compound represented by the following formula [1]: (R1 and R2 are the same or different and each represents optionally substituted aryl, Y represents N or CH, Z represents N or CH, A represents NH, NR5, O, S, or ethylene, R5 represents alkyl, D represents alkylene or alkenylene, E represents phenylene or single bond, G represents O, S, or CH2, R3 and R4 are the same or different and each represents hydrogen or alkyl, Q represents carboxy, alkoxycarbonyl, tetrazolyl, carbamoyl, or N-(alkylsulfonyl)carbamoyl), or a pharmaceutically acceptable salt thereof as an active ingredient.
Diastereoselective Synthesis of Cis-3- And 3,5-Alkylpyrrolizidines
Provot, Olivier,Celerier, Jean-Pierre,Lhommet, Gerard
, p. 371 - 376 (2007/10/03)
Cis-3 and 3,5-substituted pyrrolizidines can be prepared from β-enaminolactones. Substituted pyrrolidinoketones lead to these compounds by an amino reductive annelation with a low diastereomeric excess, but a best access to these azabicycles consists in preparing cis-2,5-disubstituted pyrrolidines which are then transformed into the expected heterocycles.
Synthesis and Kinetics of the Formation of N-Substituted Cyclic Sulfinamides from Secondary Amine Disulfides
Wagner, Barbara J.,Doi, Joyce Takahashi,Musker, W. Kenneth
, p. 4156 - 4162 (2007/10/02)
N-substituted cyclic saturated sulfinamides were prepared from two secondary amine disulfides, 3-propyl disulfide and 3-(cyclohexylamino)propyl disulfide, and two bicyclic sulfinamides were made from 2-(2-piperidyl)ethyl disulfide an
