Glycinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-L-leucyl-N-(2-chloroethyl)-

Base Information

Chemical Name:Glycinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-L-leucyl-N-(2-chloroethyl)-
CAS No.:83472-50-8
Molecular Formula:C₁₈H₃₀Cl₂N₆O₅
Molecular Weight:481.379
Hs Code.:
DSSTox Substance ID:DTXSID60232365
Wikidata:Q76156853

Synonyms:BRN 5673217;Glycinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-L-leucyl-N-(2-chloroethyl)-;1-(((2-Chloroethyl)nitrosoamino)carbonyl)-L-prolyl-L-leucyl-N-(2-chloroethyl)glycinamide;N-(Chloro-2 ethyl) N-nitrosocarbamoyl L-prolyl L-leucyl glycine chloro-2 ethylamide [French];83472-50-8;N-(Chloro-2 ethyl) N-nitrosocarbamoyl L-prolyl L-leucyl glycine chloro-2 ethylamide;C18H30Cl2N6O5;DTXSID60232365;C18-H30-Cl2-N6-O5;LS-72184

Suppliers and Price of Glycinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-L-leucyl-N-(2-chloroethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Glycinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-L-leucyl-N-(2-chloroethyl)-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.42g/cm³
XLogP3:0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:11
Exact Mass:480.1654735
Heavy Atom Count:31
Complexity:651

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)NC(=O)CNCCCl)NC(=O)C1CCCN1C(=O)N(CCCl)N=O
Isomeric SMILES:CC(C)C[C@@H](C(=O)NC(=O)CNCCCl)NC(=O)[C@@H]1CCCN1C(=O)N(CCCl)N=O

Technology Process of Glycinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-L-leucyl-N-(2-chloroethyl)-

There total 4 articles about Glycinamide, 1-(((2-chloroethyl)nitrosoamino)carbonyl)-L-prolyl-L-leucyl-N-(2-chloroethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 80354-51-4
N-(chloro-2 ethyl)N-nitrosocarbamate de trichloro-2,4,5 phenyle

: chlorhydrate de L-prolyl L-leucylglycine chloro-2 ethylamide

: 83472-50-8
N-(chloro-2 ethyl) N-nitrosocarbamoyl L-prolyl L-leucyl glycine chloro-2 ethylamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 2h; Ambient temperature;

Reference yield:

: 3469-47-4
N-carbobenzoxy L-leucylglycine chloro-2 ethylamide

: 83472-50-8
N-(chloro-2 ethyl) N-nitrosocarbamoyl L-prolyl L-leucyl glycine chloro-2 ethylamide

Guidance literature:: Multi-step reaction with 4 steps

1: H₂, cc. HCl / Pd/C / ethanol / 5 h

2: N,N-diisopropyl N-ethylamine / dimethylformamide / 2 h / Ambient temperature

3: 98 percent / H₂, cc. HCl / Pd/C / ethanol / 5 h

4: 74 percent / N,N-diisopropyl N-ethylamine / dimethylformamide / 2 h / Ambient temperature

With hydrogenchloride; hydrogen; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: (S)-2-Amino-4-methyl-pentanoic acid [(2-chloro-ethylcarbamoyl)-methyl]-amide; hydrochloride

: 83472-50-8
N-(chloro-2 ethyl) N-nitrosocarbamoyl L-prolyl L-leucyl glycine chloro-2 ethylamide

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-diisopropyl N-ethylamine / dimethylformamide / 2 h / Ambient temperature

2: 98 percent / H₂, cc. HCl / Pd/C / ethanol / 5 h

3: 74 percent / N,N-diisopropyl N-ethylamine / dimethylformamide / 2 h / Ambient temperature

With hydrogenchloride; hydrogen; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;