4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-cyclopropyl-6-methyl-4-oxo-

Base Information

Chemical Name:4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-cyclopropyl-6-methyl-4-oxo-
CAS No.:125055-61-0
Molecular Formula:C₁₃H₁₃N₃O₂
Molecular Weight:243.265
Hs Code.:
DSSTox Substance ID:DTXSID10154568
Wikidata:Q83021829
Mol file:125055-61-0.mol

Synonyms:125055-61-0;4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-cyclopropyl-6-methyl-4-oxo-;N-cyclopropyl-6-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carboxamide;N-Cyclopropyl-6-methyl-4-oxo-4H-pyrido(1,2-a)pyrimidine-3-carboxamide;N-cyclopropyl-6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide;N-cyclopropyl-2-methyl-10-oxo-1,7-diazabicyclo[4.4.0]deca-2,4,6,8-tetr aene-9-carboxamide;SCHEMBL9128690;DTXSID10154568;LS-134047

Suppliers and Price of 4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-cyclopropyl-6-methyl-4-oxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-cyclopropyl-6-methyl-4-oxo-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：66.96000
Density:1.42g/cm³
LogP:1.46990
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:243.100776666
Heavy Atom Count:18
Complexity:551

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC2=NC=C(C(=O)N12)C(=O)NC3CC3

Technology Process of 4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-cyclopropyl-6-methyl-4-oxo-

There total 3 articles about 4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-cyclopropyl-6-methyl-4-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79-22-1
methyl chloroformate

: 765-30-0
Cyclopropylamine

: 32092-27-6
6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid

: 125055-61-0
N-cyclopropyl-6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide

Guidance literature:: With sodium bicarbonate; triethylamine; In chloroform; water;

Reference yield:

: 32092-27-6
6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid

: 125055-61-0
N-cyclopropyl-6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CHCl₃ / 0.17 h / -13 °C

2: CHCl₃ / 1 h / -13 °C

With triethylamine; In chloroform;