4,4'-DITHIOBISPHENYLACETIC ACID

Base Information

• Chemical Name: 4,4'-DITHIOBISPHENYLACETIC ACID
• CAS No.: 5325-76-8
• Molecular Formula: C16H14O4S2
• Molecular Weight: 334.417
• Hs Code.: 2930909090
• Mol file: 5325-76-8.mol

Synonyms:4,4'-Dithiobisphenylacetic Acid;4,4'-dithiobisbenzeneacetic acid;

Chemical Property of 4,4'-DITHIOBISPHENYLACETIC ACID

Chemical Property:

• Melting Point: 199-202°C
• Boiling Point: 549.4°Cat760mmHg
• Flash Point: 286.1°C
• PSA: 125.20000
• Density: 1.44g/cm³
• LogP: 3.74020
• Storage Temp.: -20°C Freezer
• Solubility.: Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

4,4''-DithiobisphenylaceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A redox buffer that increases the folding rate of disulfide-containing proteins realative to traditional buffers such as glutathione and glutathione-disulfide.

Technology Process of 4,4'-DITHIOBISPHENYLACETIC ACID

There total 4 articles about 4,4'-DITHIOBISPHENYLACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-mercaptophenylacetic acid (39161-84-7) → 2-[4-[[4-(carboxymethyl)phenyl]-disulfanyl]phenyl]acetic acid (5325-76-8)

Guidance literature:

With sodium carbonate; for 36h;

DOI:10.1021/ja016938p

Reference yield:

2-methylbenzene-1,4-diol (95-71-6,96937-50-7) + 4-mercaptophenylacetic acid (39161-84-7) → 2-[4-[4,5-bis[[4-(carboxymethyl)-phenyl]sulfanyl]-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]sulfanylphenyl]acetic acid + 2-[4-[[4-(carboxymethyl)phenyl]-disulfanyl]phenyl]acetic acid (5325-76-8)

Guidance literature:

With Pycnoporus cinnabarinus laccase; In aq. acetate buffer; at 20 ℃; for 2h; pH=5; Reagent/catalyst; Overall yield = 18.8 %; Overall yield = 9.34 mg; Green chemistry; Enzymatic reaction;

DOI:10.1016/j.molcatb.2015.12.012

Reference yield:

methoxyhydroquinone (824-46-4) + 4-mercaptophenylacetic acid (39161-84-7) → 2-[4-[2-[4-(carboxymethyl)phenyl]sulfanyl-4-methoxy-3,6-dioxocyclohexa-1,4-dien-1-yl]sulfanylphenyl]acetic acid + 2-[4-[[4-(carboxymethyl)phenyl]-disulfanyl]phenyl]acetic acid (5325-76-8)

Guidance literature:

With Pycnoporus cinnabarinus laccase; In aq. acetate buffer; at 20 ℃; for 0.333333h; pH=5; Reagent/catalyst; Overall yield = 32.9 %; Overall yield = 12.37 mg; Green chemistry; Enzymatic reaction;

DOI:10.1016/j.molcatb.2015.12.012

upstream raw materials:

4-mercaptophenylacetic acid

2-methylbenzene-1,4-diol

methoxyhydroquinone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 5325-76-8 4,4'-DITHIOBISPHENYLACETIC ACID

Send

Send

Metric Ton KG G Pound L ML

Send

Send