2-Ethoxyethyl P-methoxycinnamate

Base Information

• Chemical Name: 2-Ethoxyethyl P-methoxycinnamate
• CAS No.: 104-28-9
• Molecular Formula: C14H18 O4
• Molecular Weight: 250.295
• DSSTox Substance ID: DTXSID2025264
• ChEMBL ID: CHEMBL3560776
• Mol file: 104-28-9.mol

Synonyms:DTXSID2025264;Giv Tan F;Give-Tan;Phiasol;Sundare;ethoxyethyl-p-methoxycinnamate;CHEMBL3560776;AKOS028110686

Chemical Property of 2-Ethoxyethyl P-methoxycinnamate

Chemical Property:

• Vapor Pressure: 8.25E-06mmHg at 25°C
• Melting Point: -24.9°C
• Refractive Index: 1.527
• Boiling Point: 374.6°Cat760mmHg
• Flash Point: 164.8°C
• PSA: 44.76000
• Density: 1.086g/cm³
• LogP: 2.28810
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 250.12050905
• Heavy Atom Count: 18
• Complexity: 255

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cinoxate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOCCOC(=O)C=CC1=CC=C(C=C1)OC
• Uses: Cinoxate is an organic compound used as an ingredient in some types of sunscreens. Cinoxate is an ester formed from methoxycinnamic acid and 2-ethoxyethanol. Cinoxate is a slightly yellow viscous liqu id that is insoluble in water, but miscible with alcohols, esters, and vegetable oils. Cinoxate protects skin against the sun by absorbing UV-A and UV-B rays. cinoxate (2-hydroxy-p-methoxycinnamate) is an FDA-approved sunscreen chemical with an approved usage level of 1 to 3 percent. Studies indicate it causes photosensitivity. Cinoxate is an organic compound used as an ingredient in some types of sunscreens. Cinoxate is an ester formed from methoxycinnamic acid and 2-ethoxyethanol. Cinoxate is a slightly yellow viscous liquid that is insoluble in water, but miscible with alcohols, esters, and vegetable oils.Cinoxate protects skin against the sun by absorbing UV-A and UV-B rays.

Technology Process of 2-Ethoxyethyl P-methoxycinnamate

There total 1 articles about 2-Ethoxyethyl P-methoxycinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

2-ethoxy-ethanol (110-80-5) + 3-(4'-methoxyphenyl)propenoic acid (830-09-1) → ethoxylethyl-p-methoxycinnamate (104-28-9)

Guidance literature:

With 1H-imidazole; carboxylic acid reductase from Mycobacterium marinum; ATP; magnesium chloride; In aq. buffer; at 25 ℃; for 45h; pH=10; Green chemistry; Enzymatic reaction;

DOI:10.1002/anie.202013962

upstream raw materials:

2-ethoxy-ethanol

3-(4'-methoxyphenyl)propenoic acid

Refernces