Chemical Property of 2-Ethoxyethanol
Chemical Property:
- Appearance/Colour:clear, colorless, nearly odorless liquid
- Vapor Pressure:3.8 mm Hg ( 20 °C)
- Melting Point:-100 °C
- Refractive Index:n20/D 1.407(lit.)
- Boiling Point:135.6 °C at 760 mmHg
- PKA:14.44±0.10(Predicted)
- Flash Point:44 °C
- PSA：29.46000
- Density:0.915 g/cm3
- LogP:0.01520
- Storage Temp.:Flammables area
- Solubility.:water: miscible
- Water Solubility.:miscible
- XLogP3:-0.3
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:3
- Exact Mass:90.068079557
- Heavy Atom Count:6
- Complexity:21.5
- Transport DOT Label:Flammable Liquid
- Purity/Quality:
-
99% *data from raw suppliers
2-Ethoxyethanol *data from reagent suppliers
Safty Information:
- Pictogram(s):
T
- Hazard Codes:T
- Statements:
60-61-10-20/21/22-20/22
- Safety Statements:
53-45
- MSDS Files:
-
SDS file from LookChem
Total 1 MSDS from other Authors
Useful:
- Chemical Classes:Solvents -> Glycol Ethers (E Series)
- Canonical SMILES:CCOCCO
- Inhalation Risk:A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C.
- Effects of Short Term Exposure:The substance is mildly irritating to the eyes and respiratory tract. The substance may cause effects on the central nervous system, blood, bone marrow, kidneys and liver. Exposure at high levels could cause unconsciousness. Medical observation is indicated.
- Effects of Long Term Exposure:The substance defats the skin, which may cause dryness or cracking. The substance may have effects on the blood and bone marrow. This may result in anaemia and lesions of blood cells. May cause toxicity to human reproduction or development.
-
Description
2-Ethoxyethanol is a stable, colorless, flammable liquid,
synthetically produced throughout the world. It belongs to
a larger group of glycol ether solvents. 2-Ethoxyethanol is
commercially referred to as Ethyl Cellosolve or Cellosolve,
a trademark registered by Union Carbide in 1924. It was first
synthesized to have the same chemical properties of both alcohols
and ethers (hydrophilic and lipophilic) but less volatile,
which improves production characteristics. The glycol ethers are
made by reacting anhydrous alcohols with ethylene oxide.
-
Physical properties
Clear, colorless liquid with a sweetish odor. Experimentally determined detection and recognition
odor threshold concentrations were 1.1 mg/m3 (300 ppbv) and 2.0 mg/m3 (540 ppbv), respectively
(Hellman and Small, 1974).
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Uses
2-Ethoxyethanol is widely used as an industrial solvent and
production intermediate. It is produced by the reaction of
ethylene oxide with ethanol. The glycol ethers are miscible in
polar and nonpolar solutions, which make them useful
solvents in paints and surface coatings, stains, lacquers, inks,
and dyes. Additional uses include industrial deicing,
hydraulic fluids, and cleaning agents. 2-Ethoxyethanol was
once used in cosmetic products but is no longer used due to
toxicity associated with dermal absorption. Global production
has been on the decline in recent years based on
demonstrated toxicity through oral, dermal, and inhalation
routes of exposure. The use of ethylene glycol ethers has
largely been replaced by relatively safer substitutes, primarily
propylene glycol ethers; however, their use as a solvent and
chemical process intermediate poses potential for release into
the environment. Ethylene glycol
monoethyl ether is used in varnish removers, lacquers, and as a solvent for printing
inks, duplicating fluids, and epoxy. Ethylene glycol monobutyl ether is used in
hydraulic fluids, as a coupling agent for water-based coatings, in vinyl and acrylic
paints and varnishes, and as a solvent for varnishes, enamels, spray lacquers, dry
cleaning compounds, textiles, and cosmetics. Ethylene glycol monoethyl ether (EGEE) isused as a solvent for nitrocellulose, lacquers,and varnishes; in dye baths and cleansingsolutions; and as an emulsion stabilizer. antiobesity agent pancreatic lipase inhibitor
