10,11-Dihydro-3-fluoro-alpha-methyl-11-oxodibenz(b,f)(1,4)oxazepine-8-acetic acid

Base Information

Chemical Name:10,11-Dihydro-3-fluoro-alpha-methyl-11-oxodibenz(b,f)(1,4)oxazepine-8-acetic acid
CAS No.:109823-13-4
Molecular Formula:C₁₆H₁₂FNO₄
Molecular Weight:301.274
Hs Code.:
DSSTox Substance ID:DTXSID00911369

Synonyms:BRN 5607918;10,11-Dihydro-3-fluoro-alpha-methyl-11-oxodibenz(b,f)(1,4)oxazepine-8-acetic acid;Dibenz(b,f)(1,4)oxazepine-8-acetic acid, 10,11-dihydro-3-fluoro-alpha-methyl-11-oxo-;109823-13-4;DTXSID00911369;LS-61556;2-(3-Fluoro-11-hydroxydibenzo[b,f][1,4]oxazepin-8-yl)propanoic acid

Suppliers and Price of 10,11-Dihydro-3-fluoro-alpha-methyl-11-oxodibenz(b,f)(1,4)oxazepine-8-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 10,11-Dihydro-3-fluoro-alpha-methyl-11-oxodibenz(b,f)(1,4)oxazepine-8-acetic acid

Chemical Property:

Vapor Pressure:2.37E-07mmHg at 25°C
Boiling Point:406.9°Cat760mmHg
Flash Point:199.9°C
Density:1.392g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:301.07503603
Heavy Atom Count:22
Complexity:457

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC2=C(C=C1)OC3=C(C=CC(=C3)F)C(=O)N2)C(=O)O

Technology Process of 10,11-Dihydro-3-fluoro-alpha-methyl-11-oxodibenz(b,f)(1,4)oxazepine-8-acetic acid

There total 1 articles about 10,11-Dihydro-3-fluoro-alpha-methyl-11-oxodibenz(b,f)(1,4)oxazepine-8-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51234-43-6,73933-15-0
3-amino-4-hydroxyphenyl-2-methylacetic acid

: 109823-13-4
2-(3-Fluoro-11-oxo-10,11-dihydro-dibenzo[b,f][1,4]oxazepin-8-yl)-propionic acid

Guidance literature:: With sodium hydroxide; Yield given. Multistep reaction; 1.) 2 eq. reagent, aq. MeOH; 2.) DMF, reflux;
DOI:10.1016/0223-5234(87)90013-4