2-Ethyl-10H-phenothiazine

Base Information

Chemical Name:2-Ethyl-10H-phenothiazine
CAS No.:61852-27-5
Molecular Formula:C14H13NS
Molecular Weight:227.33
Hs Code.:2934300000
European Community (EC) Number:263-274-2
NSC Number:169670
UNII:223ET7HZ45
DSSTox Substance ID:DTXSID00210829
Nikkaji Number:J306.921D
Wikidata:Q83085624
ChEMBL ID:CHEMBL4759402
Mol file:61852-27-5.mol

Synonyms:2-Ethyl-10H-phenothiazine;61852-27-5;223ET7HZ45;EINECS 263-274-2;NSC-169670;2-ethylphenothiazine;NSC169670;starbld0031608;C(C)c1ccc2Sc3ccccc3Nc2c1;UNII-223ET7HZ45;10H-Phenothiazine, 2-ethyl-;SCHEMBL7595855;CHEMBL4759402;DTXSID00210829;AKOS030255058;NSC 169670

Suppliers and Price of 2-Ethyl-10H-phenothiazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Ethylphenothiazine
500mg
$ 1735.00

TRC
2-Ethylphenothiazine
50mg
$ 295.00

Total 19 raw suppliers

Chemical Property of 2-Ethyl-10H-phenothiazine

Chemical Property:

Vapor Pressure:3E-06mmHg at 25°C
Boiling Point:388.7°Cat760mmHg
Flash Point:188.9°C
PSA：37.33000
Density:1.169g/cm³
LogP:4.59520
XLogP3:4.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:227.07687059
Heavy Atom Count:16
Complexity:243

Purity/Quality:

99%min ^*data from raw suppliers

2-Ethylphenothiazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC2=C(C=C1)SC3=CC=CC=C3N2
Uses 2-Ethylphenothiazine is an intermediate in the synthesis of Etymemazine (E938500), derivative of phenothiazine, an antibacterial agent.

Technology Process of 2-Ethyl-10H-phenothiazine

There total 3 articles about 2-Ethyl-10H-phenothiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 6631-94-3
2-acetylphenothiazine

: 61852-27-5
2-ethyl-10H-phenothiazine

Guidance literature:: 2-acetylphenothiazine; 5; With triethylsilane; In dichloromethane; at 20 ℃; for 20h;

With ammonium fluoride; sulfuric acid; at 40 ℃; for 1h;
DOI:10.1016/j.ejmech.2020.112842

Reference yield:

: 6631-94-3
2-acetylphenothiazine

: 61852-27-5
2-ethyl-10H-phenothiazine

Guidance literature:: With potassium hydroxide; hydrazine hydrate; In ethylene glycol; Heating;

Reference yield:

: 1628-29-1
10-acetyl-10H-phenothiazine

: 61852-27-5
2-ethyl-10H-phenothiazine

Guidance literature:: Multi-step reaction with 2 steps

1: (i) AlCl₃, CS₂, (ii) aq. HCl

2: KOH, aq. N₂H₄*H₂O / ethane-1,2-diol / Heating

With potassium hydroxide; hydrazine hydrate; In ethylene glycol;