1,2-Bis(3-bromophenyl)-1,1,2,2-tetramethyldisilane

Base Information

• Chemical Name: 1,2-Bis(3-bromophenyl)-1,1,2,2-tetramethyldisilane
• CAS No.: 143952-73-2
• Molecular Formula: C16H20Br2Si2
• Molecular Weight: 428.314
• DSSTox Substance ID: DTXSID60567265
• Wikidata: Q82453094
• Mol file: 143952-73-2.mol

Synonyms:143952-73-2;1,2-Bis(3-bromophenyl)-1,1,2,2-tetramethyldisilane;DTXSID60567265

Chemical Property of 1,2-Bis(3-bromophenyl)-1,1,2,2-tetramethyldisilane

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 427.94498
• Heavy Atom Count: 20
• Complexity: 298

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C1=CC(=CC=C1)Br)[Si](C)(C)C2=CC(=CC=C2)Br

Technology Process of 1,2-Bis(3-bromophenyl)-1,1,2,2-tetramethyldisilane

There total 1 articles about 1,2-Bis(3-bromophenyl)-1,1,2,2-tetramethyldisilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-dichlorotetramethylsilane (4342-61-4) + 1,3-dibromobenzene (108-36-1) → 1,2-bis(3-bromophenyl)-1,1,2,2-tetramethyldisilane (143952-73-2)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1.) Et₂O, hexane, -78 deg C, 1 h, 2.) Et₂O, hexane, from -78 deg C to RT, 1 h;

DOI:10.1021/ja00073a006

Reference yield: 73.0%

tert-butylnitroso dimer (31107-20-7,117894-51-6) + 1,2-bis(3-bromophenyl)-1,1,2,2-tetramethyldisilane (143952-73-2) → 1,2-bis[3-(N-hydroxy-tert-butylamino)phenyl]-1,1,2,2-tetramethyldisilane (402588-72-1)

Guidance literature:

1,2-bis(3-bromophenyl)-1,1,2,2-tetramethyldisilane; With n-butyllithium; In diethyl ether; hexane; at -78 - 20 ℃;

tert-butylnitroso dimer; In tetrahydrofuran; diethyl ether; hexane; at -78 - 20 ℃; Further stages.;

DOI:10.1021/ol017093p

Reference yield:

1,2-bis(3-bromophenyl)-1,1,2,2-tetramethyldisilane (143952-73-2) → C24H38N2O2Si2

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / diethyl ether; hexane / -78 - 20 °C

1.2: 73 percent / diethyl ether; hexane; tetrahydrofuran / -78 - 20 °C

2.1: 21 percent / silver(I) oxide / diethyl ether / 20 °C

With n-butyllithium; silver(l) oxide; In diethyl ether; hexane;

DOI:10.1021/ol017093p

upstream raw materials:

1,2-dichlorotetramethylsilane

1,3-dibromobenzene

Downstream raw materials:

1,2-bis[3-(N-hydroxy-tert-butylamino)phenyl]-1,1,2,2-tetramethyldisilane