Phenol, 4-(2-aminoethyl)-2-fluoro-, hydrobromide

Base Information

Chemical Name:Phenol, 4-(2-aminoethyl)-2-fluoro-, hydrobromide
CAS No.:113676-36-1
Molecular Formula:C8H10 F N O . Br H
Molecular Weight:236.084
Hs Code.:
DSSTox Substance ID:DTXSID20150516

Synonyms:4-(2-Aminoethyl)-2-fluorophenol hydrobromide;Phenol, 4-(2-aminoethyl)-2-fluoro-, hydrobromide;2-(3-Fluoro-4-hydroxyphenyl)ethylamine hydrobromide;113676-36-1;C8H10NO.BrH;C8-H10-N-O.Br-H;SCHEMBL9510772;DTXSID20150516;LS-103909

Suppliers and Price of Phenol, 4-(2-aminoethyl)-2-fluoro-, hydrobromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Phenol, 4-(2-aminoethyl)-2-fluoro-, hydrobromide

Chemical Property:

Vapor Pressure:0.012mmHg at 25°C
Boiling Point:252.6°Cat760mmHg
Flash Point:106.6°C
Density:g/cm³
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:235.00080
Heavy Atom Count:12
Complexity:121

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1CCN)F)O.Br

Technology Process of Phenol, 4-(2-aminoethyl)-2-fluoro-, hydrobromide

There total 5 articles about Phenol, 4-(2-aminoethyl)-2-fluoro-, hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 458-40-2
2-(3-fluoro-4-methoxyphenyl)ethan-1-amine

: 113676-36-1
2-(3-fluoro-4-hydroxyphenyl)ethylamine hydrobromide

Guidance literature:: With hydrogen bromide; at 125 ℃; for 3h;

Reference yield:

: 404-90-0
2-(3-fluoro-4-methoxyphenyl)acetonitrile

: 113676-36-1
2-(3-fluoro-4-hydroxyphenyl)ethylamine hydrobromide

Guidance literature:: Multi-step reaction with 2 steps

1: 46 percent / LiAlH₄ / diethyl ether / 1.) R_.T_. 3 h., 2.) reflux 1 h.

2: 52 percent / hydrobromic acid / 6 h / Heating

With lithium aluminium tetrahydride; hydrogen bromide; In diethyl ether;

Reference yield:

: 351-54-2
3-fluoro-p-anisaldehyde

: 113676-36-1
2-(3-fluoro-4-hydroxyphenyl)ethylamine hydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / ammonium acetate / acetic acid / 2 h / 120 °C

2: 95 percent / LiAlH₄ / tetrahydrofuran / 16 h / Ambient temperature

3: 74 percent / 48percent HBr / 3 h / 125 °C

With ammonium acetate; lithium aluminium tetrahydride; hydrogen bromide; In tetrahydrofuran; acetic acid;