404-90-0

Basic information

• Product Name: 3-FLUORO-4-METHOXYPHENYLACETONITRILE
• Synonyms: 3-FLUORO-4-METHOXYBENZYL CYANIDE;3-FLUORO-4-METHOXYPHENYLACETONITRILE;3-Fluoro-4-methoxyphenylacetonitrile98%;2-(3-fluoro-4-methoxyphenyl)acetonitrile;2-(3-fluoro-4-methoxy-phenyl)acetonitrile;2-(3-fluoro-4-methoxy-phenyl)ethanenitrile;4-(Cyanomethyl)-2-fluoroanisole;Benzeneacetonitrile, 3-fluoro-4-Methoxy-
• CAS NO: 404-90-0
• Molecular Formula: C₉H₈FNO
• Molecular Weight: 165.16
• Product Categories: Fluorine series
• Mol File: 404-90-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 46-48°C
• Boiling Point: 270.6 °C at 760 mmHg
• Flash Point: 117.5 °C
• Appearance: /
• Density: 1.148 g/cm³
• Vapor Pressure: 0.00676mmHg at 25°C
• Refractive Index: 1.501
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-FLUORO-4-METHOXYPHENYLACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-FLUORO-4-METHOXYPHENYLACETONITRILE(404-90-0)
• EPA Substance Registry System: 3-FLUORO-4-METHOXYPHENYLACETONITRILE(404-90-0)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 3439
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 404-90-0(Hazardous Substances Data)

Usage

General Description

3-Fluoro-4-methoxyphenylacetonitrile is a chemical compound with the molecular formula C9H8FNO and a molecular weight of 163.16 g/mol. It is a nitrile compound that contains a fluorine atom and a methoxy group attached to a phenyl ring. 3-FLUORO-4-METHOXYPHENYLACETONITRILE is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also utilized in the manufacture of fine chemicals and in research and development. 3-Fluoro-4-methoxyphenylacetonitrile is important in organic synthesis and has various applications in the chemical industry.

InChI:InChI=1/C9H8FNO/c1-12-9-3-2-7(4-5-11)6-8(9)10/h2-3,6H,4H2,1H3

Upstream product

• 102-86-3 tri-n-hexylamine 
• 331-61-3 3-fluoro-4-methoxybenzyl bromide 
• 351-54-2 3-fluoro-p-anisaldehyde 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 321-28-8 1-fluoro-2-methoxybenzene 
• 351-52-0 3-fluoro-4-methoxybenzyl chloride 
• 143-33-9 sodium cyanide 

Downstream Products

• 451-73-0 3c-benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-acrylonitrile 
• 580-78-9 2-(3-fluoro-4-methoxy-phenyl)-3c-phenyl-acrylonitrile 
• 72222-29-8 α-isopropyl-3-fluoro-4-methoxyphenylacetonitrile 
• 128495-61-4 N-propionyl-2-(3-fluoro-4-methoxyphenyl)ethylamine 
• 118958-82-0 N-acetyl-2-(3-fluoro-4-methoxyphenyl)ethylamine 

Relevant articles and documents

Fluorine substituted methoxyphenylalkyl amides as potent melatonin receptor agonists?

A series of fluorine substituted methoxyphenylalkyl amides were prepared with different orientations of the fluorine and methoxy groups with respect to the alkylamide side chain and with alkyl sides of differing lengths (n = 1-3). β-Dimethyl and α-methyl

COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

Pyrazinone thrombin inhibitors

Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure: for example: