1-(2-(2-(diphenyl)methoxy)ethyl)-4-(3-phenylpropyl)homopiperazine

Base Information

• Chemical Name: 1-(2-(2-(diphenyl)methoxy)ethyl)-4-(3-phenylpropyl)homopiperazine
• CAS No.: 150151-14-7
• Molecular Formula: C₂₉H₃₆N₂O
• Molecular Weight: 428.618
• Mol file: 150151-14-7.mol

Synonyms:LR 1111

Chemical Property of 1-(2-(2-(diphenyl)methoxy)ethyl)-4-(3-phenylpropyl)homopiperazine

Chemical Property:

• Vapor Pressure: 4.37E-12mmHg at 25°C
• Boiling Point: 548.6°Cat760mmHg
• PKA: 9.20±0.10(Predicted)
• Flash Point: 143.9°C
• PSA: 15.71000
• Density: 1.055g/cm³
• LogP: 5.30890

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2-(2-(diphenyl)methoxy)ethyl)-4-(3-phenylpropyl)homopiperazine

There total 4 articles about 1-(2-(2-(diphenyl)methoxy)ethyl)-4-(3-phenylpropyl)homopiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[4-(2-Benzhydryloxy-ethyl)-[1,4]diazepan-1-yl]-3-phenyl-propan-1-one (1028302-99-9) → LR 1111 (150151-14-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 24h; Yield given; Ambient temperature;

DOI:10.1021/jm960305h

Reference yield:

1,1-Diphenylmethanol (91-01-0) → LR 1111 (150151-14-7)

Guidance literature:

Multi-step reaction with 4 steps

1: H₂SO₄ / toluene

2: 71 percent / K₂CO₃ / toluene / 24 h / Heating

3: CHCl₃ / 24 h / Ambient temperature

4: LiAlH₄ / tetrahydrofuran / 24 h / Ambient temperature

With lithium aluminium tetrahydride; sulfuric acid; potassium carbonate; In tetrahydrofuran; chloroform; toluene;

DOI:10.1021/jm960305h

Reference yield:

1,1'-[(2-chloroethoxy)methylene]bis-benzene (32669-06-0) → LR 1111 (150151-14-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 71 percent / K₂CO₃ / toluene / 24 h / Heating

2: CHCl₃ / 24 h / Ambient temperature

3: LiAlH₄ / tetrahydrofuran / 24 h / Ambient temperature

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; chloroform; toluene;

DOI:10.1021/jm960305h

upstream raw materials:

1-[4-(2-Benzhydryloxy-ethyl)-[1,4]diazepan-1-yl]-3-phenyl-propan-1-one

1,1-Diphenylmethanol

1,1'-[(2-chloroethoxy)methylene]bis-benzene

1-[2-(diphenylmethoxy)ethyl]homopiperazine

Refernces