Technology Process of 2-Octenoic acid,
8-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,5-dimethylphenyl]-, ethyl
ester, (Z)-
There total 5 articles about 2-Octenoic acid,
8-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,5-dimethylphenyl]-, ethyl
ester, (Z)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) t-BuLi / 1.) pentane, ether, -78 deg C, 1 h, 2.) THF, -78 deg C, 1 h
2: 99 percent / H2 / 5percent Pd/C / ethanol / 12 h / 760 Torr
3: 1.) DMSO, oxalyl chloride, 2.) Et3N / 1.) CH2Cl2, -50 deg C, 15 min, 2.) CH2Cl2, 0 deg C, 1 h
4: diethyl ether / 8 h / Ambient temperature
With
oxalyl dichloride; hydrogen; tert.-butyl lithium; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal;
In
diethyl ether; ethanol;
DOI:10.1021/jo00051a038
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) t-BuLi / 1.) pentane, ether, -78 deg C, 1 h, 2.) THF, -78 deg C, 1 h
2: 99 percent / H2 / 5percent Pd/C / ethanol / 12 h / 760 Torr
3: 1.) DMSO, oxalyl chloride, 2.) Et3N / 1.) CH2Cl2, -50 deg C, 15 min, 2.) CH2Cl2, 0 deg C, 1 h
4: diethyl ether / 8 h / Ambient temperature
With
oxalyl dichloride; hydrogen; tert.-butyl lithium; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal;
In
diethyl ether; ethanol;
DOI:10.1021/jo00051a038
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 99 percent / H2 / 5percent Pd/C / ethanol / 12 h / 760 Torr
2: 1.) DMSO, oxalyl chloride, 2.) Et3N / 1.) CH2Cl2, -50 deg C, 15 min, 2.) CH2Cl2, 0 deg C, 1 h
3: diethyl ether / 8 h / Ambient temperature
With
oxalyl dichloride; hydrogen; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal;
In
diethyl ether; ethanol;
DOI:10.1021/jo00051a038
