N1-(2,2,6,6-tetraMethylpiperidin-4-yl)-N2-p-tolyloxalaMide

Base Information

Chemical Name:N1-(2,2,6,6-tetraMethylpiperidin-4-yl)-N2-p-tolyloxalaMide
CAS No.:144217-65-2
Molecular Formula:C₁₈H₂₇N₃O₂
Molecular Weight:317.431
Hs Code.:
Mol file:144217-65-2.mol

Synonyms:N-(2,2,6,6-Tetramethyl-piperidin-4-yl)-N'-p-tolyl-oxalamide;

Suppliers and Price of N1-(2,2,6,6-tetraMethylpiperidin-4-yl)-N2-p-tolyloxalaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
YYA-021
10mg
$ 160.00

Medical Isotopes, Inc.
YYA-021
50 mg
$ 890.00

Medical Isotopes, Inc.
YYA-021
10 mg
$ 290.00

DC Chemicals
YYA-021 >98%
250 mg
$ 900.00

Crysdot
YYA-021 98+%
5mg
$ 48.00

Crysdot
YYA-021 98+%
10mg
$ 77.00

Crysdot
YYA-021 98+%
50mg
$ 273.00

ChemScene
YYA-021 99.83%
100mg
$ 340.00

ChemScene
YYA-021 99.83%
10mg
$ 90.00

ChemScene
YYA-021 99.83%
5mg
$ 75.00

Total 19 raw suppliers

Chemical Property of N1-(2,2,6,6-tetraMethylpiperidin-4-yl)-N2-p-tolyloxalaMide

Chemical Property:

PKA:11.61±0.70(Predicted)
PSA：70.23000
Density:1.11±0.1 g/cm3(Predicted)
LogP:3.15160
Solubility.:Limited solubility

Purity/Quality:

99%, ^*data from raw suppliers

YYA-021 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses YYA-021 is a small molecule CD4 mimic HIV entry inhibitor that can suppress competitively the interaction between an HIV-1 envelope glycoprotein gp120 and a cellular surface protein CD4.

Technology Process of N1-(2,2,6,6-tetraMethylpiperidin-4-yl)-N2-p-tolyloxalaMide

There total 4 articles about N1-(2,2,6,6-tetraMethylpiperidin-4-yl)-N2-p-tolyloxalaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 36768-62-4
4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE

: 42868-89-3
2-oxo-2-(p-tolylamino)acetic acid

: 144217-65-2
YYA-021

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1016/j.bmcl.2009.10.098

Reference yield:

: 106-49-0,12221-03-3
p-toluidine

: 144217-65-2
YYA-021

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / 0.5 h / 20 °C / Sealed tube

2: acetonitrile / 6 h / 100 °C

With N-ethyl-N,N-diisopropylamine; In acetonitrile;
DOI:10.1021/acscombsci.5b00091