2-Propanone, 1-(2,5-dimethoxyphenyl)-

Base Information

• Chemical Name: 2-Propanone, 1-(2,5-dimethoxyphenyl)-
• CAS No.: 14293-24-4
• Molecular Formula: C11H14 O3
• Molecular Weight: 194.23
• Hs Code.: 2914509090
• European Community (EC) Number: 604-322-8
• NSC Number: 108872
• DSSTox Substance ID: DTXSID20884743
• Nikkaji Number: J266.771A
• Wikidata: Q82863387
• Mol file: 14293-24-4.mol

Synonyms:14293-24-4;1-(2,5-dimethoxyphenyl)propan-2-one;2-Propanone, 1-(2,5-dimethoxyphenyl)-;(2,5-Dimethoxyphenyl)acetone;2-Propanone, (2,5-dimethoxy)phenyl-;MFCD00026239;2,5-dimethoxyphenylacetone;2,5-Dimethoxyphenyl acetone;NSC108872;SCHEMBL5743959;1-(2,5-Dimethoxyphenyl)acetone;DTXSID20884743;1-(2,5-Dimethoxyphenyl)acetone #;AKOS006343056;NSC 108872;NSC-108872;NS-01888;EN300-1999632

Chemical Property of 2-Propanone, 1-(2,5-dimethoxyphenyl)-

Chemical Property:

• Vapor Pressure: 0.00211mmHg at 25°C
• Boiling Point: 290.1°C at 760 mmHg
• Flash Point: 120.1°C
• PSA: 35.53000
• Density: 1.056g/cm³
• LogP: 1.83530
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 194.094294304
• Heavy Atom Count: 14
• Complexity: 191

Purity/Quality:

98% ^*data from raw suppliers

1-(2,5-dimethoxyphenyl)propan-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(=O)CC1=C(C=CC(=C1)OC)OC

Technology Process of 2-Propanone, 1-(2,5-dimethoxyphenyl)-

There total 12 articles about 2-Propanone, 1-(2,5-dimethoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-(2,5-Dimethoxy-phenyl)-propan-2-one O-methyl-oxime → 1-(2',5'-dimethoxyphenyl)propan-2-one (14293-24-4)

Guidance literature:

With hydrogenchloride; In methanol; at 65 ℃; for 10h;

DOI:10.1039/c39840000795

Reference yield: 82.0%

2,5-dimethoxy-β-methyl-β-nitrostyrene (134040-27-0) → 1-(2',5'-dimethoxyphenyl)propan-2-one (14293-24-4)

Guidance literature:

With iron; acetic acid; at 60 ℃; for 3h;

DOI:10.1134/S1070428020040181

Reference yield: 63.0%

2-(β-hydroxypropyl)-1,4-dimethoxybenzene (40180-96-9) → 1-(2',5'-dimethoxyphenyl)propan-2-one (14293-24-4)

Guidance literature:

With jones reagent; In acetone; at 0 ℃; for 1h;

DOI:10.1021/jo970570q

upstream raw materials:

(2,5-dimethoxyphenyl)acetic acid

(E)-1,4-dimethoxy-2-(2-nitroprop-1-en-1-yl) benzene

1-bromo-2,5-dimethoxybenzene

chloroacetone

Downstream raw materials:

3-(2,5-dimethoxyphenyl)-2-oximinopropane

N,N-dimethyl-2-(2,5-dimethoxyphenyl)isopropylamine

4-(2,5-Dimethoxy-phenyl)-3-hydroxy-3-methyl-butyric acid ethyl ester

3-(2',5'-dimethoxyphenyl)butan-2-one