Methanimidic acid, N-(chloroacetyl)-, 2-(4-nitrophenyl)hydrazide

Base Information

• Chemical Name: Methanimidic acid, N-(chloroacetyl)-, 2-(4-nitrophenyl)hydrazide
• CAS No.: 144479-33-4
• Molecular Formula: C9H9ClN4O3
• Molecular Weight: 256.648
• Mol file: 144479-33-4.mol

Synonyms:

Chemical Property of Methanimidic acid, N-(chloroacetyl)-, 2-(4-nitrophenyl)hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanimidic acid, N-(chloroacetyl)-, 2-(4-nitrophenyl)hydrazide

There total 1 articles about Methanimidic acid, N-(chloroacetyl)-, 2-(4-nitrophenyl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4-nitrophenylhydrazone (100-16-3) → 2-Chloro-N-[(4-nitro-phenyl)-hydrazonomethyl]-acetamide (144479-33-4)

Guidance literature:

In ethanol; for 0.0833333h; Heating;

DOI:10.1002/ardp.19923250813

Reference yield: 87.0%

2-Chloro-N-[(4-nitro-phenyl)-hydrazonomethyl]-acetamide (144479-33-4) → 5-Chloromethyl-1-(4-nitro-phenyl)-1H-[1,2,4]triazole (114370-75-1)

Guidance literature:

With PPA; at 130 ℃; for 0.25h;

DOI:10.1002/ardp.19923250813

Reference yield:

2-Chloro-N-[(4-nitro-phenyl)-hydrazonomethyl]-acetamide (144479-33-4) → 5-aminomethyl-1-(4-nitrophenyl)-1,2,4-triazole (144479-47-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 87 percent / polyphosphoric acid / 0.25 h / 130 °C

2: 77 percent / K₂CO₃ / dimethylformamide / 3 h / 160 - 180 °C

3: 57 percent / 70percent hydrazine hydrate / ethanol / 3 h / Heating

With PPA; potassium carbonate; hydrazine hydrate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1002/ardp.19923250813

upstream raw materials:

4-nitrophenylhydrazone

Downstream raw materials:

5-Chloromethyl-1-(4-nitro-phenyl)-1H-[1,2,4]triazole

5-aminomethyl-1-(4-nitrophenyl)-1,2,4-triazole

5-phthalimidomethyl-1-(4-nitrophenyl)-1,2,4-triazole