Pyridazino(3,4-b)(1,4)benzoxazepine, 10,11-dihydro-2-(4-methyl-1-piperazinyl)-11-(p-tolyl)-

Base Information

Chemical Name:Pyridazino(3,4-b)(1,4)benzoxazepine, 10,11-dihydro-2-(4-methyl-1-piperazinyl)-11-(p-tolyl)-
CAS No.:70301-63-2
Molecular Formula:C₂₃H₂₅N₅O
Molecular Weight:387.484
Hs Code.:
DSSTox Substance ID:DTXSID90220578
Nikkaji Number:J78.833C
Wikidata:Q83097867

Synonyms:2-(4-Methyl-1-piperazinyl)-11-(p-tolyl)-10,11-dihydro-pyridazino(3,4-b)(1,4)benzoxazepine;Pyridazino(3,4-b)(1,4)benzoxazepine, 10,11-dihydro-2-(4-methyl-1-piperazinyl)-11-(p-tolyl)-;70301-63-2;C28H25N5O;DTXSID90220578;LS-129642;5,6-Dihydro-3-(4-methyl-1-piperazinyl)-5-(p-tolyl)pyridazino[3,4-b][1,4]benzoxazepine

Suppliers and Price of Pyridazino(3,4-b)(1,4)benzoxazepine, 10,11-dihydro-2-(4-methyl-1-piperazinyl)-11-(p-tolyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Pyridazino(3,4-b)(1,4)benzoxazepine, 10,11-dihydro-2-(4-methyl-1-piperazinyl)-11-(p-tolyl)-

Chemical Property:

Vapor Pressure:6.65E-16mmHg at 25°C
Boiling Point:632.5°Cat760mmHg
Flash Point:336.3°C
Density:1.225g/cm³
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:387.20591044
Heavy Atom Count:29
Complexity:531

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N2CC3=CC=CC=C3OC4=NN=C(C=C42)N5CCN(CC5)C

Technology Process of Pyridazino(3,4-b)(1,4)benzoxazepine, 10,11-dihydro-2-(4-methyl-1-piperazinyl)-11-(p-tolyl)-

There total 2 articles about Pyridazino(3,4-b)(1,4)benzoxazepine, 10,11-dihydro-2-(4-methyl-1-piperazinyl)-11-(p-tolyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14674-88-5
2-((p-toluidino)methyl)phenol

: 70301-63-2
3-(4-methyl-piperazin-1-yl)-5-p-tolyl-5,6-dihydro-benzo[f]pyridazino[3,4-b][1,4]oxazepine

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / ethanol / Heating

2: KI, cyclohexanol / Heating

With potassium carbonate; potassium iodide; cyclohexanol; In ethanol;
DOI:10.1007/BF00772046