1-Pyrrolidinecarboxylic acid, 2-(phenylmethyl)-, methyl ester

Base Information

Chemical Name:1-Pyrrolidinecarboxylic acid, 2-(phenylmethyl)-, methyl ester
CAS No.:144688-80-2
Molecular Formula:C13H17NO2
Molecular Weight:219.283
Hs Code.:
DSSTox Substance ID:DTXSID90448452
Nikkaji Number:J1.483.719A
Mol file:144688-80-2.mol

Synonyms:144688-80-2;1-Pyrrolidinecarboxylic acid, 2-(phenylmethyl)-, methyl ester;DTXSID90448452;2-Benzylpyrrolidine-1-carboxylic acid methyl ester

Suppliers and Price of 1-Pyrrolidinecarboxylic acid, 2-(phenylmethyl)-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 1-Pyrrolidinecarboxylic acid, 2-(phenylmethyl)-, methyl ester

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:219.125928785
Heavy Atom Count:16
Complexity:236

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)N1CCCC1CC2=CC=CC=C2

Technology Process of 1-Pyrrolidinecarboxylic acid, 2-(phenylmethyl)-, methyl ester

There total 9 articles about 1-Pyrrolidinecarboxylic acid, 2-(phenylmethyl)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 56475-88-8
methyl 2-methoxypyrrolidine-1-carboxylate

: 6921-34-2
benzylmagnesium chloride

: 144688-80-2
α-benzyl-N-methoxycarbonylpyrrolidine

Guidance literature:: methyl 2-methoxypyrrolidine-1-carboxylate; benzylmagnesium chloride; In dichloromethane; at -78 ℃; for 1h; Inert atmosphere;

With boron trifluoride diethyl etherate; In dichloromethane; at -78 ℃; Inert atmosphere;
DOI:10.1002/chem.200903512

Reference yield: 77.0%

: 855595-94-7
N-methoxycarbonyl-2-trimethylsilylpyrrolidine

: 100-39-0
benzyl bromide

: 144688-80-2
α-benzyl-N-methoxycarbonylpyrrolidine

Guidance literature:: N-methoxycarbonyl-2-trimethylsilylpyrrolidine; With trifluorormethanesulfonic acid; tetrabutylammonium tetrafluoroborate; In dichloromethane; at -78 ℃; Electrolysis;

benzyl bromide; With bis(tri-n-butyltin); In dichloromethane; at -20 ℃; for 1.5h;
DOI:10.1021/ja0511218

Reference yield: 74.0%

: 144688-71-1
α-benzyl-α-cyano-N-methoxycarbonylpyrrolidine

: 144688-80-2
α-benzyl-N-methoxycarbonylpyrrolidine

Guidance literature:: With tetraethylammonium tosylate; In acetonitrile; carbon rod anode; zinc cathode; 4.5 F/mol;
DOI:10.1016/S0040-4020(01)80493-2