Benzene, 1-bromo-2,4,5-trimethoxy-3-(1-methylethyl)-

Base Information

Chemical Name:Benzene, 1-bromo-2,4,5-trimethoxy-3-(1-methylethyl)-
CAS No.:144707-40-4
Molecular Formula:C12H17BrO3
Molecular Weight:289.169
Hs Code.:
DSSTox Substance ID:DTXSID40474706
Nikkaji Number:J681.243K
Wikidata:Q82304813
Mol file:144707-40-4.mol

Synonyms:144707-40-4;Benzene, 1-bromo-2,4,5-trimethoxy-3-(1-methylethyl)-;1-bromo-2,4,5-trimethoxy-3-propan-2-ylbenzene;1-bromo-3-isopropyl-2,4,5-trimethoxybenzene;DTXSID40474706;1,2,4-Trimethoxy-3-isopropyl-5-bromobenzene

Suppliers and Price of Benzene, 1-bromo-2,4,5-trimethoxy-3-(1-methylethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzene, 1-bromo-2,4,5-trimethoxy-3-(1-methylethyl)-

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:288.03611
Heavy Atom Count:16
Complexity:210

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=C(C(=CC(=C1OC)Br)OC)OC

Technology Process of Benzene, 1-bromo-2,4,5-trimethoxy-3-(1-methylethyl)-

There total 8 articles about Benzene, 1-bromo-2,4,5-trimethoxy-3-(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 60241-78-3
3-(1-methylethyl)-1,2,4-trimethoxybenzene

: 144707-40-4
5-Bromo-1,2,4-trimethoxy-3-isopropylbenzene

Guidance literature:: With N-Bromosuccinimide; In acetonitrile;
DOI:10.1002/ejoc.200600361

Reference yield:

: 135-77-3
1,2,4-trimethoxy-benzene

: 144707-40-4
5-Bromo-1,2,4-trimethoxy-3-isopropylbenzene

Guidance literature:: Multi-step reaction with 4 steps

1: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / 0 °C / Inert atmosphere

2: tin(II) trifluoromethanesulfonate / dichloromethane / 6 h / 40 °C / Inert atmosphere

3: hydrogen; palladium on activated charcoal / 12 h / 20 °C / 760.05 Torr

4: N-Bromosuccinimide / dichloromethane / 2 h / 20 °C / Inert atmosphere

With N-Bromosuccinimide; tin(II) trifluoromethanesulfonate; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; palladium on activated charcoal; hydrogen; In dichloromethane;
DOI:10.1021/acs.joc.5b01345

Reference yield:

: 60241-76-1
3-(1-methyl-1-hydroxyethyl)-1,2,4-trimethoxybenzene

: 144707-40-4
5-Bromo-1,2,4-trimethoxy-3-isopropylbenzene

Guidance literature:: Multi-step reaction with 3 steps

1: tin(II) trifluoromethanesulfonate / dichloromethane / 6 h / 40 °C / Inert atmosphere

2: hydrogen; palladium on activated charcoal / 12 h / 20 °C / 760.05 Torr

3: N-Bromosuccinimide / dichloromethane / 2 h / 20 °C / Inert atmosphere

With N-Bromosuccinimide; tin(II) trifluoromethanesulfonate; palladium on activated charcoal; hydrogen; In dichloromethane;
DOI:10.1021/acs.joc.5b01345