5-(6,8-Diaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

Base Information

Chemical Name:5-(6,8-Diaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
CAS No.:13389-09-8
Molecular Formula:C₁₀H₁₄N₆O₃
Molecular Weight:266.26
Hs Code.:2934999090
NSC Number:101167
DSSTox Substance ID:DTXSID50928321
Mol file:13389-09-8.mol

Synonyms:8-amino-2'-deoxyadenosine;8-amino-dA

Suppliers and Price of 5-(6,8-Diaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-Amino-2’-deoxyadenosine
25mg
$ 505.00

Biosynth Carbosynth
8-Amino-2’-deoxyadenosine
25 mg
$ 375.00

Biosynth Carbosynth
8-Amino-2’-deoxyadenosine
10 mg
$ 180.00

Biosynth Carbosynth
8-Amino-2’-deoxyadenosine
5 mg
$ 100.00

Biosynth Carbosynth
8-Amino-2’-deoxyadenosine
2 mg
$ 60.00

Biosynth Carbosynth
8-Amino-2’-deoxyadenosine
50 mg
$ 600.00

American Custom Chemicals Corporation
8-AMINO-2'-DEOXYADENOSINE 98.00%
0.5G
$ 1636.80

Total 8 raw suppliers

Chemical Property of 5-(6,8-Diaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

Chemical Property:

Boiling Point:698.2°Cat760mmHg
PKA:13.76±0.60(Predicted)
Flash Point:376°C
PSA：145.33000
Density:2.08g/cm³
LogP:-0.20620
XLogP3:-0.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:266.11273833
Heavy Atom Count:19
Complexity:334

Purity/Quality:

99.3% ^*data from raw suppliers

8-Amino-2’-deoxyadenosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(OC1N2C3=NC=NC(=C3N=C2N)N)CO)O
Uses 8-Amino-2’-deoxyadenosine is derived from 8-Azido-2’-deoxyadenosine which is needed for the preparation of oligonucleotides. Also, it is base-paired with 2’-deoxythymidine which may have important significance for designing novel DNA duplexes and triplexes.

Technology Process of 5-(6,8-Diaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

There total 4 articles about 5-(6,8-Diaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 131265-35-5
8-Azido-2'-deoxyadenosine

: 13389-09-8
8-amino-2'-deoxyadenosine

Guidance literature:: With methylamine; In 1,4-dioxane; at 55 ℃;
DOI:10.1081/NCN-120019521

Reference yield:

: 951-78-0,63844-76-8
2'-deoxyuridine

: 28128-33-8
8-Aminoadenine

: 13389-09-8
8-amino-2'-deoxyadenosine

Guidance literature:: at 37 ℃; for 16h; alginate gel-entrapped cells of auxotrophic thymine-dependent strain of E_. coli, ammonium acetate buffer pH 5.7;
DOI:10.1135/cccc19942303