Piperidine, 1-(1,3-dioxo-4-phenylbutyl)-

Base Information

Chemical Name:Piperidine, 1-(1,3-dioxo-4-phenylbutyl)-
CAS No.:146380-08-7
Molecular Formula:C15H19NO2
Molecular Weight:245.321
Hs Code.:
DSSTox Substance ID:DTXSID40455878
Wikidata:Q82278032
Mol file:146380-08-7.mol

Synonyms:146380-08-7;Piperidine, 1-(1,3-dioxo-4-phenylbutyl)-;4-phenyl-1-piperidin-1-ylbutane-1,3-dione;SCHEMBL6692812;DTXSID40455878;AKOS015905153;FT-0754149;4-oxo-1-phenyl-4-(1-piperidinyl)-2-butanone

Suppliers and Price of Piperidine, 1-(1,3-dioxo-4-phenylbutyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Piperidine, 1-(1,3-dioxo-4-phenylbutyl)-

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:245.141578849
Heavy Atom Count:18
Complexity:289

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C(=O)CC(=O)CC2=CC=CC=C2

Technology Process of Piperidine, 1-(1,3-dioxo-4-phenylbutyl)-

There total 1 articles about Piperidine, 1-(1,3-dioxo-4-phenylbutyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 110-89-4
piperidine

: 66696-84-2
5-(1-hydroxy-2-phenylethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione

: 146380-08-7
4-oxo-1-phenyl-4-piperidin-1-ylbutan-2-one

Guidance literature:: In benzene; for 4h; Heating;
DOI:10.1055/s-1992-26338

Reference yield: 35.0%

: 6485-52-5
L-phenylglycine amide

: 146380-08-7
4-oxo-1-phenyl-4-piperidin-1-ylbutan-2-one

: 679789-08-3
(2S)-2-{[(1Z)-1-benzyl-3-oxo-3-piperidin-1-ylprop-1-en-1-yl]amino}-2-phenylacetamide

Guidance literature:: With acetic acid; In methanol; at 40 ℃; for 72h;
DOI:10.1021/ja038812t

Reference yield:

: 146380-08-7
4-oxo-1-phenyl-4-piperidin-1-ylbutan-2-one

: 679789-19-6
(2S)-2-{[(1R)-1-benzyl-3-oxo-3-piperidin-1-ylpropyl]amino}-2-phenylacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / acetic acid / methanol / 72 h / 40 °C

2: 88 percent / H₂ / PtO₂ / tetrahydrofuran / 24 h / 4654.33 Torr

With hydrogen; acetic acid; platinum(IV) oxide; In tetrahydrofuran; methanol;
DOI:10.1021/ja038812t