7-(2,6-Dimethyl-4-pyridyl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

Base Information

Chemical Name:7-(2,6-Dimethyl-4-pyridyl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
CAS No.:40034-50-2
Molecular Formula:C19H18N2O3
Molecular Weight:322.364
Hs Code.:
European Community (EC) Number:254-764-7
DSSTox Substance ID:DTXSID90193096
Nikkaji Number:J261.505C
Wikidata:Q83065814
ChEMBL ID:CHEMBL85724
Mol file:40034-50-2.mol

Synonyms:40034-50-2;DIMETHYLROSOXACIN;7-(2,6-Dimethyl-4-pyridyl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid;EINECS 254-764-7;7-(2,6-Dimethylpyridin-4-yl)-1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;CHEMBL85724;SCHEMBL9720500;DTXSID90193096;NLQFSXNYFCJEGX-UHFFFAOYSA-N;7-(2,6-dimethyl-4-pyridinyl)-1-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Suppliers and Price of 7-(2,6-Dimethyl-4-pyridyl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 7-(2,6-Dimethyl-4-pyridyl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

Chemical Property:

Vapor Pressure:2.73E-10mmHg at 25°C
Boiling Point:486.8°Cat760mmHg
Flash Point:248.2°C
PSA：72.19000
Density:1.259g/cm³
LogP:3.39840
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:322.13174244
Heavy Atom Count:24
Complexity:535

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN1C=C(C(=O)C2=C1C=C(C=C2)C3=CC(=NC(=C3)C)C)C(=O)O

Technology Process of 7-(2,6-Dimethyl-4-pyridyl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

There total 5 articles about 7-(2,6-Dimethyl-4-pyridyl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

: 40034-74-0
7-(2,6-dimethyl-pyridin-4-yl)-1-ethyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

: 40034-50-2
1-ethyl-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid

Guidance literature:: With potassium hydroxide; for 1h; Heating;
DOI:10.1002/jhet.5570210655

Reference yield:

: 40034-51-3
4-(3-aminophenyl)-2,6-dimethylpyridine

: 40034-50-2
1-ethyl-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 78 percent / 0.13 h / 130 °C

2: 85 percent / various solvent(s) / 0.2 h / Heating; heating in Dowtherm

3: 65 percent / 1) potassium carbonate / dimethylformamide / 1) 60 deg C, 15 min; 2) stirring 1 h;

4: 24 percent / aq. 10percent KOH / 1 h / Heating

With potassium hydroxide; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570210655

Reference yield:

: 40034-52-4
diethyl ({[3-(2,6-dimethyl-4-pyridyl)phenyl]amino}methylene)malonate

: 40034-50-2
1-ethyl-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / various solvent(s) / 0.2 h / Heating; heating in Dowtherm

2: 65 percent / 1) potassium carbonate / dimethylformamide / 1) 60 deg C, 15 min; 2) stirring 1 h;

3: 24 percent / aq. 10percent KOH / 1 h / Heating

With potassium hydroxide; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570210655