Ethyl 7-(2,6-dimethyl-4-pyridyl)-1,4-dihydro-4-oxoquinoline-3-carboxylate

Base Information

Chemical Name:Ethyl 7-(2,6-dimethyl-4-pyridyl)-1,4-dihydro-4-oxoquinoline-3-carboxylate
CAS No.:40034-49-9
Molecular Formula:C19H18N2O3
Molecular Weight:322.364
Hs Code.:2933990090
European Community (EC) Number:254-763-1
DSSTox Substance ID:DTXSID30193095
Nikkaji Number:J261.504E
Wikidata:Q83065813
Mol file:40034-49-9.mol

Synonyms:40034-49-9;Ethyl 7-(2,6-dimethyl-4-pyridyl)-1,4-dihydro-4-oxoquinoline-3-carboxylate;EINECS 254-763-1;ethyl 7-(2,6-dimethylpyridin-4-yl)-4-oxo-1H-quinoline-3-carboxylate;Ethyl 7-(2,6-dimethylpyridin-4-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate;DTXSID30193095;7-(2,6-Dimethyl-4-pyridinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester

Suppliers and Price of Ethyl 7-(2,6-dimethyl-4-pyridyl)-1,4-dihydro-4-oxoquinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of Ethyl 7-(2,6-dimethyl-4-pyridyl)-1,4-dihydro-4-oxoquinoline-3-carboxylate

Chemical Property:

Vapor Pressure:1.18E-08mmHg at 25°C
Boiling Point:460.3°Cat760mmHg
Flash Point:232.2°C
PSA：72.05000
Density:1.215g/cm³
LogP:3.38360
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:322.13174244
Heavy Atom Count:24
Complexity:521

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=CNC2=C(C1=O)C=CC(=C2)C3=CC(=NC(=C3)C)C

Technology Process of Ethyl 7-(2,6-dimethyl-4-pyridyl)-1,4-dihydro-4-oxoquinoline-3-carboxylate

There total 4 articles about Ethyl 7-(2,6-dimethyl-4-pyridyl)-1,4-dihydro-4-oxoquinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 40034-52-4
diethyl ({[3-(2,6-dimethyl-4-pyridyl)phenyl]amino}methylene)malonate

: 40034-49-9
7-(2,6-dimethyl-pyridin-4-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

Guidance literature:: In various solvent(s); for 0.2h; Heating; heating in Dowtherm;
DOI:10.1002/jhet.5570210655

Reference yield:

: 40034-51-3
4-(3-aminophenyl)-2,6-dimethylpyridine

: 40034-49-9
7-(2,6-dimethyl-pyridin-4-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / 0.13 h / 130 °C

2: 85 percent / various solvent(s) / 0.2 h / Heating; heating in Dowtherm

In various solvent(s);
DOI:10.1002/jhet.5570210655

Reference yield:

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 40034-49-9
7-(2,6-dimethyl-pyridin-4-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / 0.13 h / 130 °C

2: 85 percent / various solvent(s) / 0.2 h / Heating; heating in Dowtherm

In various solvent(s);
DOI:10.1002/jhet.5570210655