1-(2-Hydroxyphenyl)prop-2-en-1-one

Base Information

• Chemical Name: 1-(2-Hydroxyphenyl)prop-2-en-1-one
• CAS No.: 1467-39-6
• Molecular Formula: C9H8O2
• Molecular Weight: 148.161
• DSSTox Substance ID: DTXSID70560227
• Nikkaji Number: J799.462A
• Wikidata: Q82443237
• Mol file: 1467-39-6.mol

Synonyms:1-(2-Hydroxyphenyl)prop-2-en-1-one;1467-39-6;2-Propen-1-one, 1-(2-hydroxyphenyl)-;Acryloyl-Phenole;SCHEMBL9315349;DTXSID70560227;CS-0267124;EN300-1828628

Chemical Property of 1-(2-Hydroxyphenyl)prop-2-en-1-one

Chemical Property:

• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 148.052429494
• Heavy Atom Count: 11
• Complexity: 163

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CC(=O)C1=CC=CC=C1O

Technology Process of 1-(2-Hydroxyphenyl)prop-2-en-1-one

There total 10 articles about 1-(2-Hydroxyphenyl)prop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3-hydroxy-1-(2-hydroxyphenyl)propan-1-one (137709-27-4) → 1-(2-hydroxyphenyl)-2-propen-1-one (1467-39-6)

Guidance literature:

With sulfuric acid; In benzene; for 1.33333h; Heating;

DOI:10.1248/cpb.39.2106

Reference yield: 74.0%

o-Allylphenol (1745-81-9) → 1-(2-hydroxyphenyl)-2-propen-1-one (1467-39-6)

Guidance literature:

With 3,6-bis(triphenylphosphonium)cyclohexene peroxodisulfate; In water; acetonitrile; for 0.416667h; Heating;

DOI:10.1081/SCC-120006010

Reference yield: 16.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + o-hydroxyacetophenone (118-93-4,104809-67-8) → 1-(2-hydroxyphenyl)-2-propen-1-one (1467-39-6)

Guidance literature:

With hydrogenchloride; N,N-dimethylammonium chloride; In isopropyl alcohol; for 1h; Heating;

DOI:10.1021/jo960163z

upstream raw materials:

3-hydroxy-1-(2-hydroxyphenyl)propan-1-one

formaldehyd

o-hydroxyacetophenone

o-Allylphenol

Downstream raw materials:

2'-Hydroxy-3-methoxypropiophenon

3-hydroxydibenzofuran

2-(2-hydroxyphenyl)-3-methylquinoline

2,3-dihydro-4H-1-benzopyran-4-one