methyl 2-(acetylamino)-2-deoxy-3,4-di-O-methyl-6-O-tritylhexopyranoside

Base Information

• Chemical Name: methyl 2-(acetylamino)-2-deoxy-3,4-di-O-methyl-6-O-tritylhexopyranoside
• CAS No.: 69892-56-4
• Molecular Formula: C₃₀H₃₅NO₆
• Molecular Weight: 505.611
• Mol file: 69892-56-4.mol

Synonyms:

Chemical Property of methyl 2-(acetylamino)-2-deoxy-3,4-di-O-methyl-6-O-tritylhexopyranoside

Chemical Property:

• Vapor Pressure: 1.49E-16mmHg at 25°C
• Boiling Point: 645.5°Cat760mmHg
• Flash Point: 344.2°C
• Density: 1.19g/cm³

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 2-(acetylamino)-2-deoxy-3,4-di-O-methyl-6-O-tritylhexopyranoside

There total 2 articles about methyl 2-(acetylamino)-2-deoxy-3,4-di-O-methyl-6-O-tritylhexopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl iodide (74-88-4) + methyl 6-O-triphenylmethyl-2-acetamido-2-deoxy-α-D-glucopyranoside (50908-05-9) → methyl-(2-acetylamino-O3,O4-dimethyl-O6-trityl-2-deoxy-α-D-glucopyranoside) (69892-56-4)

Guidance literature:

With silver(l) oxide;

DOI:10.1021/ja01138a045

Reference yield:

→ methyl-(2-acetylamino-O3,O4-dimethyl-O6-trityl-2-deoxy-α-D-glucopyranoside) (69892-56-4)

Guidance literature:

Pyranosid XIX, Dimethylsulfat;

Reference yield:

methyl-(2-acetylamino-O3,O4-dimethyl-O6-trityl-2-deoxy-α-D-glucopyranoside) (69892-56-4) → 2-benzyloxycarbonylamino-O3,O4-dimethyl-2-deoxy-D-glucose

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid; water

2: aqueous hydrochloric acid

3: H₂O; NaHCO₃

With hydrogenchloride; water; sodium hydrogencarbonate; acetic acid;

DOI:10.1021/ja01138a045

upstream raw materials:

methyl iodide

methyl 6-O-triphenylmethyl-2-acetamido-2-deoxy-α-D-glucopyranoside

Downstream raw materials:

Methyl 2-acetamido-2-deoxy-3,4-di-O-methyl-α-D-glucopyranoside