1-acetyl-5-(3,4-dimethoxyphenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole

Base Information

Chemical Name:1-acetyl-5-(3,4-dimethoxyphenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole
CAS No.:152432-17-2
Molecular Formula:C17H18N2O3S
Molecular Weight:330.40100
Hs Code.:
Mol file:152432-17-2.mol

Synonyms:1-[5-(3,4-Dimethoxy-phenyl)-3-thiophen-2-yl-4,5-dihydro-pyrazol-1-yl]-ethanone;

Suppliers and Price of 1-acetyl-5-(3,4-dimethoxyphenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-acetyl-5-(3,4-dimethoxyphenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole

Chemical Property:

Melting Point:160 °C
PSA：79.37000
LogP:2.83640

Purity/Quality:

Safty Information:

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Technology Process of 1-acetyl-5-(3,4-dimethoxyphenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole

There total 3 articles about 1-acetyl-5-(3,4-dimethoxyphenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 74441-58-0,137444-52-1
(E)-3-(3,4-dimethoxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one

: 64-19-7,77671-22-8
acetic acid

: 152432-17-2
1-acetyl-5-(3,4-dimethoxyphenyl)-3-(thienyl)-2-pyrazoline

Guidance literature:: With hydrazine hydrate; Reflux;
DOI:10.14233/ajchem.2014.16428

Reference yield:

: 88-15-3,97511-16-5
2-Acetylthiophene

: 152432-17-2
1-acetyl-5-(3,4-dimethoxyphenyl)-3-(thienyl)-2-pyrazoline

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / methanol / 4 h / 0 - 5 °C

2: NH₂NH₂ / Heating

With sodium hydroxide; hydrazine; In methanol;

Reference yield:

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 152432-17-2
1-acetyl-5-(3,4-dimethoxyphenyl)-3-(thienyl)-2-pyrazoline

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / methanol / 4 h / 0 - 5 °C

2: NH₂NH₂ / Heating

With sodium hydroxide; hydrazine; In methanol;