1H-Pyrrole-2,5-dione, 3,4-bis(2-methyl-1H-indol-3-yl)-1-(phenylmethyl)-

Base Information

Chemical Name:1H-Pyrrole-2,5-dione, 3,4-bis(2-methyl-1H-indol-3-yl)-1-(phenylmethyl)-
CAS No.:152537-89-8
Molecular Formula:C29H23N3O2
Molecular Weight:445.521
Hs Code.:
DSSTox Substance ID:DTXSID60472340
Nikkaji Number:J2.732.834B
Wikidata:Q82301221
Mol file:152537-89-8.mol

Synonyms:152537-89-8;1H-Pyrrole-2,5-dione, 3,4-bis(2-methyl-1H-indol-3-yl)-1-(phenylmethyl)-;DTXSID60472340

Suppliers and Price of 1H-Pyrrole-2,5-dione, 3,4-bis(2-methyl-1H-indol-3-yl)-1-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Pyrrole-2,5-dione, 3,4-bis(2-methyl-1H-indol-3-yl)-1-(phenylmethyl)-

Chemical Property:

XLogP3:5.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:445.17902698
Heavy Atom Count:34
Complexity:788

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C2=CC=CC=C2N1)C3=C(C(=O)N(C3=O)CC4=CC=CC=C4)C5=C(NC6=CC=CC=C65)C

Technology Process of 1H-Pyrrole-2,5-dione, 3,4-bis(2-methyl-1H-indol-3-yl)-1-(phenylmethyl)-

There total 1 articles about 1H-Pyrrole-2,5-dione, 3,4-bis(2-methyl-1H-indol-3-yl)-1-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 95-20-5
2-methyl-1H-indole

: 91026-00-5
N-benzyl-2,3-dibromo-maleimide

: 152537-89-8
3,4-bis-(3-indolyl-2-methyl)-1-benzyl-pyrrole-2,5-dione

Guidance literature:: 2-methyl-1H-indole; With ethylmagnesium chloride; In tetrahydrofuran; toluene; at 45 ℃; for 0.75h; Inert atmosphere;

N-benzyl-2,3-dibromo-maleimide; In tetrahydrofuran; toluene; for 12h; Inert atmosphere; Reflux;
DOI:10.1016/j.tet.2009.04.090

Reference yield: 76.0%

: 4549-31-9
1,7-dibromoheptane

: 152537-89-8
3,4-bis-(3-indolyl-2-methyl)-1-benzyl-pyrrole-2,5-dione

: 20-benzyl-23,24-dimethyl-,7,8,9,10,11,12-hexahydro-6H,18H-5,21:13,18-dimethenodibenzo[j,p]pyrrolo[3,4-m][1,9]diazacycloheptadecine-19,21-dione

Guidance literature:: 3,4-bis-(3-indolyl-2-methyl)-1-benzyl-pyrrole-2,5-dione; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

1,7-dibromoheptane; In N,N-dimethyl-formamide; at 23 ℃; for 24h;
DOI:10.1039/b405010j

Reference yield: 63.0%

: 4101-68-2
1,10-dibromodecane

: 152537-89-8
3,4-bis-(3-indolyl-2-methyl)-1-benzyl-pyrrole-2,5-dione

: 712352-31-3
23-benzyl-26,27-dimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-22H-5,25:16,21-dimethenodibenzo[b,h]pyrrolo[3,4-e][1,10]diazacycloicosine-22,24-dione

Guidance literature:: 3,4-bis-(3-indolyl-2-methyl)-1-benzyl-pyrrole-2,5-dione; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

1,10-dibromodecane; In N,N-dimethyl-formamide; at 23 ℃; for 24h;
DOI:10.1039/b405010j