(4S,5R)-2-Chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine

Base Information

Chemical Name:(4S,5R)-2-Chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine
CAS No.:154097-86-6
Molecular Formula:C₁₀H₁₃ClNOP
Molecular Weight:229.646
Hs Code.:
DSSTox Substance ID:DTXSID30531150
Nikkaji Number:J1.927.508F
Mol file:154097-86-6.mol

Synonyms:154097-86-6;(4S,5R)-2-Chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine;SCHEMBL6376474;DTXSID30531150

Suppliers and Price of (4S,5R)-2-Chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,5R)-2-Chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:229.0423287
Heavy Atom Count:14
Complexity:199

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(OP(N1C)Cl)C2=CC=CC=C2
Isomeric SMILES:C[C@H]1[C@H](OP(N1C)Cl)C2=CC=CC=C2

Technology Process of (4S,5R)-2-Chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine

There total 9 articles about (4S,5R)-2-Chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

: 67069-59-4
N-methyl-[(1S,2R)-(2-phenyl-1-methyl-2-trimethylsilyloxy)]ethylamine

: 61739-41-1,146683-57-0,154097-86-6
(2R,4S,5R)-2-Chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine

Guidance literature:: With pyridine; phosphorus trichloride; In chloroform-d1; at -65 - 20 ℃; for 26h; Inert atmosphere;
DOI:10.1080/10426500902719222

Reference yield: 80.0%

: 299-42-3,7009-81-6,90-83-5,6912-63-6
ephedrine

: 61739-41-1,146683-57-0,154097-86-6
(4S,5R)-2-chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine

Guidance literature:: With triethylamine; phosphorus trichloride; In toluene; for 16h; Ambient temperature;
DOI:10.1039/c39920001771

Reference yield: 75.0%

: 299-42-3,7009-81-6,90-83-5,6912-63-6
ephedrine

: 61739-41-1,146683-57-0,154097-86-6
(2R,4S,5R)-2-Chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine

Guidance literature:: With 4-methyl-morpholine; phosphorus trichloride; In toluene; a) -78 deg C, 3 h, b) 22 deg C, 12 h;
DOI:10.1016/0957-4166(95)00122-6