(3-Chloro-4-fluorophenyl)thiourea

Base Information

Chemical Name:(3-Chloro-4-fluorophenyl)thiourea
CAS No.:154371-25-2
Molecular Formula:C7H6ClFN2S
Molecular Weight:204.655
Hs Code.:2930909090
European Community (EC) Number:808-751-3
DSSTox Substance ID:DTXSID20351607
Wikidata:Q82128148
Mol file:154371-25-2.mol

Synonyms:(3-chloro-4-fluorophenyl)thiourea;154371-25-2;3-chloro-4-fluorophenylthiourea;1-(3-Chloro-4-fluorophenyl)-2-thiourea;N-(3-chloro-4-fluorophenyl)thiourea;1-(3-chloro-4-fluorophenyl)thiourea;(3-Chloro-4-fluoro-phenyl)-thiourea;HMS1762F02;SCHEMBL3299680;4-fluoro-3-chlorophenylthiourea;SCHEMBL22263165;DTXSID20351607;(3-chloro-4-luorophenyl)thiourea;CHEBI:195044;OVJVZVPEMXLKOE-UHFFFAOYSA-N;MFCD01571081;STL510500;AKOS001063428;BS-4152;CCG-245853;SB77441;C3137;CS-0211976;EN300-06323;T70335;1-(3-Chloro-4-fluorophenyl)thiourea, AldrichCPR;A927181;SR-01000044252;SR-01000044252-1;Z56923300

Suppliers and Price of (3-Chloro-4-fluorophenyl)thiourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(3-Chloro-4-fluorophenyl)-2-thiourea
250mg
$ 55.00

TCI Chemical
(3-Chloro-4-fluorophenyl)thiourea >98.0%(HPLC)
5g
$ 330.00

TCI Chemical
(3-Chloro-4-fluorophenyl)thiourea >98.0%(HPLC)
1g
$ 110.00

SynQuest Laboratories
1-(3-Chloro-4-fluorophenyl)-2-thiourea
1 g
$ 68.00

Sigma-Aldrich
1-(3-Chloro-4-fluorophenyl)thiourea Aldrich
1g
$ 194.00

Crysdot
(3-Chloro-4-fluorophenyl)thiourea 95+%
25g
$ 489.00

BLDpharm
(3-Chloro-4-fluorophenyl)thiourea 98%
5g
$ 174.00

BLDpharm
(3-Chloro-4-fluorophenyl)thiourea 98%
1g
$ 50.00

Apolloscientific
3-Chloro-4-fluorophenylthiourea
1g
$ 61.00

Apolloscientific
3-Chloro-4-fluorophenylthiourea
5g
$ 182.00

Total 15 raw suppliers

Chemical Property of (3-Chloro-4-fluorophenyl)thiourea

Chemical Property:

Melting Point:179.0 to 183.0 °C
Boiling Point:295.9±50.0 °C(Predicted)
PKA:11.78±0.70(Predicted)
PSA：74.68000
Density:1.530±0.06 g/cm3(Predicted)
LogP:2.92830
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:203.9924252
Heavy Atom Count:12
Complexity:179

Purity/Quality:

97% ^*data from raw suppliers

1-(3-Chloro-4-fluorophenyl)-2-thiourea ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1NC(=S)N)Cl)F

Technology Process of (3-Chloro-4-fluorophenyl)thiourea

There total 6 articles about (3-Chloro-4-fluorophenyl)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 17356-08-0
thiourea

: 3-chloro-4-fluoroaniline hydrochloride

: 154371-25-2
1-(3-chloro-4-fluorophenyl)thiourea

Guidance literature:: With hydrogenchloride; acetic acid; In water; for 12h; Reflux;
DOI:10.1002/jhet.728

Reference yield: 58.0%

: 367-21-5
3-chloro-4-fluorophenylamine

: 17356-08-0
thiourea

: 154371-25-2
1-(3-chloro-4-fluorophenyl)thiourea

Guidance literature:: With choline chloride; tin(ll) chloride; at 130 ℃; for 8h; Green chemistry;
DOI:10.1039/d1nj01827b

Reference yield:

: 367-21-5
3-chloro-4-fluorophenylamine

: 154371-25-2
1-(3-chloro-4-fluorophenyl)thiourea

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetone / 0.25 h / Heating

1.2: acetone / 0.5 h / Heating

2.1: aq. NaOH

With sodium hydroxide; In acetone;
DOI:10.1016/S0223-5234(02)01447-2