2-[2-(2-Nitrophenyl)ethynyl]pyridine

Base Information

Chemical Name:2-[2-(2-Nitrophenyl)ethynyl]pyridine
CAS No.:155372-21-7
Molecular Formula:C13H8N2O2
Molecular Weight:224.219
Hs Code.:
DSSTox Substance ID:DTXSID40372773
Nikkaji Number:J1.922.038I
Wikidata:Q82160646
Mol file:155372-21-7.mol

Synonyms:1-(2-Pyridyl)-2-(2-nitrobenzyl)alkyne;155372-21-7;2-[2-(2-nitrophenyl)ethynyl]pyridine;Pyridine, 2-[2-(2-nitrophenyl)ethynyl]-;DTXSID40372773;2-[(2-Nitrophenyl)ethynyl]pyridine;AKOS004904948;1-(2-Pyridinylethynyl)-2-nitrobenzene;FT-0674226;J-009189

Suppliers and Price of 2-[2-(2-Nitrophenyl)ethynyl]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(2-Pyridyl)-2-(2-nitrobenzyl)alkyne
250mg
$ 140.00

Medical Isotopes, Inc.
1-(2-Pyridyl)-2-(2-nitrobenzyl)alkyne
200 mg
$ 860.00

American Custom Chemicals Corporation
1-(2-PYRIDYL)-2-(2-NITROBENZYL)ALKYNE 95.00%
2G
$ 1683.00

American Custom Chemicals Corporation
1-(2-PYRIDYL)-2-(2-NITROBENZYL)ALKYNE 95.00%
200MG
$ 671.00

Total 3 raw suppliers

Chemical Property of 2-[2-(2-Nitrophenyl)ethynyl]pyridine

Chemical Property:

Boiling Point:409.6±25.0 °C(Predicted)
PKA:1.81±0.19(Predicted)
PSA：58.71000
Density:1.30±0.1 g/cm3(Predicted)
LogP:2.91280
Solubility.:Chloroform, Dichloromethane, Ethyl Acetate
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:224.058577502
Heavy Atom Count:17
Complexity:336

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Pyridyl)-2-(2-nitrobenzyl)alkyne ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C#CC2=CC=CC=N2)[N+](=O)[O-]
Uses 1-(2-Pyridyl)-2-(2-nitrobenzyl)alkyne is used in the efficient synthesis of isatogens and anthranils.

Technology Process of 2-[2-(2-Nitrophenyl)ethynyl]pyridine

There total 8 articles about 2-[2-(2-Nitrophenyl)ethynyl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1945-84-2
2-ethynylpyridine

: 609-73-4
o-nitroiodobenzene

: 155372-21-7
2-((2-nitrophenyl)ethynyl)pyridine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine; In N,N-dimethyl-formamide; at 20 ℃; for 6h; Inert atmosphere;
DOI:10.1002/ejoc.201000769

Reference yield:

: 681463-39-8
2-(α,β-dichloro-2-nitro-phenethyl)-pyridine

: 155372-21-7
2-((2-nitrophenyl)ethynyl)pyridine

Guidance literature:: With potassium hydroxide;
DOI:10.1002/hlca.19440270184

Reference yield:

: 77340-84-2
2-(o-nitrostyryl)-pyridine

: 155372-21-7
2-((2-nitrophenyl)ethynyl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrachloromethane; chlorine

2: ethanolic KOH-solution

With tetrachloromethane; potassium hydroxide; chlorine;
DOI:10.1002/hlca.19440270184