Thieno[3,4-d]oxazole, 4,6-dihydro-2-phenyl-, 5,5-dioxide

Base Information

Chemical Name:Thieno[3,4-d]oxazole, 4,6-dihydro-2-phenyl-, 5,5-dioxide
CAS No.:156144-31-9
Molecular Formula:C11H9NO3S
Molecular Weight:235.263
Hs Code.:
DSSTox Substance ID:DTXSID10434559
Nikkaji Number:J583.152K
Wikidata:Q82249015
Mol file:156144-31-9.mol

Synonyms:156144-31-9;Thieno[3,4-d]oxazole, 4,6-dihydro-2-phenyl-, 5,5-dioxide;DTXSID10434559;2-Phenyl-4,6-dihydrothieno[3,4-d]oxazole 5,5-dioxide

Suppliers and Price of Thieno[3,4-d]oxazole, 4,6-dihydro-2-phenyl-, 5,5-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Thieno[3,4-d]oxazole, 4,6-dihydro-2-phenyl-, 5,5-dioxide

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:235.03031432
Heavy Atom Count:16
Complexity:356

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=C(CS1(=O)=O)OC(=N2)C3=CC=CC=C3

Technology Process of Thieno[3,4-d]oxazole, 4,6-dihydro-2-phenyl-, 5,5-dioxide

There total 4 articles about Thieno[3,4-d]oxazole, 4,6-dihydro-2-phenyl-, 5,5-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 156144-24-0
3-Benzamido-4-oxotetrahydrothiophene 1,1-dioxide

: 156144-31-9
2-Phenyl-4,6-dihydro-thieno[3,4-d]oxazole 5,5-dioxide

Guidance literature:: With phosphorus pentachloride; In chloroform; for 1h; Ambient temperature;
DOI:10.1021/jo00087a049

Reference yield:

: 98-88-4
benzoyl chloride

: 156144-31-9
2-Phenyl-4,6-dihydro-thieno[3,4-d]oxazole 5,5-dioxide

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / Et₃N / CH₂Cl₂ / 1.) 0 deg C, 30 min, 2.) r.t., 12 h

2: NaHCO₃ / methanol / 12 h / Ambient temperature

3: Jones' reagent / acetone / 2 h

4: 68 percent / PCl₅ / CHCl₃ / 1 h / Ambient temperature

With jones' reagent; phosphorus pentachloride; sodium hydrogencarbonate; triethylamine; In methanol; dichloromethane; chloroform; acetone;
DOI:10.1021/jo00087a049

Reference yield:

: 1027294-21-8
N-(4-Hydroxy-1,1-dioxo-tetrahydro-1λ⁶-thiophen-3-yl)-benzamide

: 156144-31-9
2-Phenyl-4,6-dihydro-thieno[3,4-d]oxazole 5,5-dioxide

Guidance literature:: Multi-step reaction with 2 steps

1: Jones' reagent / acetone / 2 h

2: 68 percent / PCl₅ / CHCl₃ / 1 h / Ambient temperature

With jones' reagent; phosphorus pentachloride; In chloroform; acetone;
DOI:10.1021/jo00087a049