[(3R)-1-benzyl-2,5-dioxopyrrolidin-3-yl] acetate

Base Information

Chemical Name:[(3R)-1-benzyl-2,5-dioxopyrrolidin-3-yl] acetate
CAS No.:156150-59-3
Molecular Formula:C13H13NO4
Molecular Weight:247.251
Hs Code.:
DSSTox Substance ID:DTXSID60363704
Nikkaji Number:J708.024G
Wikidata:Q82147451
Mol file:156150-59-3.mol

Synonyms:156150-59-3;[(3R)-1-benzyl-2,5-dioxopyrrolidin-3-yl] acetate;(3R)-1-Benzyl-3-(acetyloxy)pyrrolidine-2,5-dione;(R)-1-Benzyl-2,5-dioxopyrrolidin-3-yl acetate;AC1LTQB5;starbld0010691;SCHEMBL3593084;DTXSID60363704

Suppliers and Price of [(3R)-1-benzyl-2,5-dioxopyrrolidin-3-yl] acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of [(3R)-1-benzyl-2,5-dioxopyrrolidin-3-yl] acetate

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:247.08445790
Heavy Atom Count:18
Complexity:360

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1CC(=O)N(C1=O)CC2=CC=CC=C2
Isomeric SMILES:CC(=O)O[C@@H]1CC(=O)N(C1=O)CC2=CC=CC=C2

Technology Process of [(3R)-1-benzyl-2,5-dioxopyrrolidin-3-yl] acetate

There total 9 articles about [(3R)-1-benzyl-2,5-dioxopyrrolidin-3-yl] acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 108-24-7
acetic anhydride

: 165657-63-6
(3R)-1-benzyl-3-hydroxypyrrolidine-2,5-dione

: 156150-59-3,173353-34-9
(R)-(+)-3-(acetoxy)-1-(phenylmethyl)-2,5-pyrrolidinedione

Guidance literature:: With pyridine; at 20 ℃; for 23h;
DOI:10.1016/j.bioorg.2014.04.007

Reference yield:

: C₁₃H₁₅NO₅

: 156150-59-3,173353-34-9
(R)-(+)-3-(acetoxy)-1-(phenylmethyl)-2,5-pyrrolidinedione

Guidance literature:: With acetyl chloride; In toluene; for 2.5h; Heating / reflux;

Reference yield:

: (3R,4SR)-3-acetoxy-4-bromo-2,5-pyrrolidinedione

: 2142-06-5
1-(phenylmethyl)-2,5-pyrrolidinedione

: 136137-85-4
(3R,4R)-1-benzyl-2,5-dioxopyrrolidine-3,4-diyl diacetate

: 156150-59-3,173353-34-9
(R)-(+)-3-(acetoxy)-1-(phenylmethyl)-2,5-pyrrolidinedione

Guidance literature:: With hydrogen; palladium on activated charcoal; In 1,4-dioxane; water; for 1.25h; under 1520 Torr; Yield given. Yields of byproduct given; Ambient temperature;
DOI:10.3987/com-95-7301