5alpha-CHOLANIC ACID-3alpha-OL-6-ONE

Base Information

Chemical Name:5alpha-CHOLANIC ACID-3alpha-OL-6-ONE
CAS No.:2393-61-5
Molecular Formula:C₂₄H₃₈O₄
Molecular Weight:390.563
Hs Code.:
European Community (EC) Number:636-626-1
Mol file:2393-61-5.mol

Synonyms:2393-61-5;5-Beta-cholanic acid-3-alpha-ol-6-one;3-ALPHA-HYDROXY-6-KETOCHOLANIC ACID;5alpha-CHOLANIC ACID-3alpha-OL-6-ONE;CHEBI:182882;5?-Cholanic Acid-3?-ol-6-one;4-(3-hydroxy-10,13-dimethyl-6-oxo-1,2,3,4,5,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl)pentanoic acid;PD034945;3-ALPHA-HYDROXY-6-KETOCHOLANICACID;FT-0636742;FT-0714170;J-015287

Suppliers and Price of 5alpha-CHOLANIC ACID-3alpha-OL-6-ONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-β-CholanicAcid-3α-ol-6-one
250mg
$ 485.00

American Custom Chemicals Corporation
3-ALPHA-HYDROXY-6-KETOCHOLANIC ACID 95.00%
100MG
$ 766.04

American Custom Chemicals Corporation
3-ALPHA-HYDROXY-6-KETOCHOLANIC ACID 95.00%
25MG
$ 651.79

American Custom Chemicals Corporation
5BETA-CHOLANIC ACID-3ALPHA-OL-6-ONE 95.00%
5MG
$ 454.42

Total 8 raw suppliers

Chemical Property of 5alpha-CHOLANIC ACID-3alpha-OL-6-ONE

Chemical Property:

Vapor Pressure:3.42E-14mmHg at 25°C
Melting Point:164 °C (acetone)
Boiling Point:545.9°C at 760 mmHg
Flash Point:298°C
PSA：74.60000
Density:1.124g/cm³
LogP:4.68610
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), methanol (Slightly)
XLogP3:4.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:390.27700969
Heavy Atom Count:28
Complexity:645

Purity/Quality:

99% ^*data from raw suppliers

5-β-CholanicAcid-3α-ol-6-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 22-26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCC(=O)O)C1CCC2C1(CCC3C2CC(=O)C4C3(CCC(C4)O)C)C
Uses 5-β-Cholanic Acid-3α-ol-6-one is derived from α-Hyodeoxycholic Acid (H998100), which is isolated from pig bile. Antitumor agent.

Technology Process of 5alpha-CHOLANIC ACID-3alpha-OL-6-ONE

There total 12 articles about 5alpha-CHOLANIC ACID-3alpha-OL-6-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 83-49-8
Hyodeoxycholic Acid

: 10573-17-8,106439-47-8,106498-92-4,135503-49-0,2393-61-5
6-Ketolithocholic acid

Guidance literature:: With N-Bromosuccinimide; In water; acetone; at 20 ℃; for 2h; Darkness;

Reference yield: 88.0%

: 2862-62-6
3α-ol-6-oxo-5β-24-cholanoic acid methyl ester

: 10573-17-8,106439-47-8,106498-92-4,135503-49-0,2393-61-5
6-Ketolithocholic acid

Guidance literature:: With sodium hydroxide; In methanol; at 50 ℃; for 3h; pH=> 13;

Reference yield:

: 2868-48-6
methyl hyodeoxycholate

: 10573-17-8,106439-47-8,106498-92-4,135503-49-0,2393-61-5
6-Ketolithocholic acid

Guidance literature:: Multi-step reaction with 3 steps

1: Jones reagent / acetone / 1 h / 0 - 5 °C

2: sodium tetrahydroborate / methanol / 0.5 h / 0 - 20 °C

3: sodium hydroxide / methanol / 3 h / 50 °C / pH > 13

With sodium tetrahydroborate; Jones reagent; sodium hydroxide; In methanol; acetone;