1-[(4-Hydroxy-3,5-diMethylbenzoyl)oxy]-2,5-pyrrolidinedione

Base Information

• Chemical Name: 1-[(4-Hydroxy-3,5-diMethylbenzoyl)oxy]-2,5-pyrrolidinedione
• CAS No.: 158788-56-8
• Molecular Formula: C13H13NO5
• Molecular Weight: 263.25
• Mol file: 158788-56-8.mol

Synonyms:2,5-Pyrrolidinedione,1-[(4-hydroxy-3,5-dimethylbenzoyl)oxy];

Chemical Property of 1-[(4-Hydroxy-3,5-diMethylbenzoyl)oxy]-2,5-pyrrolidinedione

Chemical Property:

• Boiling Point: 457.9±55.0 °C(Predicted)
• PKA: 8.25±0.25(Predicted)
• PSA: 83.91000
• Density: 1.41±0.1 g/cm3(Predicted)
• LogP: 1.16770
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99.90% ^*data from raw suppliers

1-[(4-Hydroxy-3,5-dimethylbenzoyl)oxy]-2,5-pyrrolidinedione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Intermediate in the synthesis of long emission wavelength chemiluminescent compounds.

Technology Process of 1-[(4-Hydroxy-3,5-diMethylbenzoyl)oxy]-2,5-pyrrolidinedione

There total 1 articles about 1-[(4-Hydroxy-3,5-diMethylbenzoyl)oxy]-2,5-pyrrolidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.5%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + 3,5-dimethyl-4-hydroxybenzoic acid (4919-37-3) → 1-((4-hydroxy-3,5-dimethylbenzoyl)oxy)pyrrolidine-2,5-dione (158788-56-8)

Guidance literature:

With dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 0 - 5 ℃;

Reference yield: 75.0%

1-((4-hydroxy-3,5-dimethylbenzoyl)oxy)pyrrolidine-2,5-dione (158788-56-8) + C21H35N5O8 → C30H43N5O10

Guidance literature:

With sodium hydrogencarbonate; In water; N,N-dimethyl-formamide; at 0 ℃; for 2h;

Reference yield: 73.0%

1-((4-hydroxy-3,5-dimethylbenzoyl)oxy)pyrrolidine-2,5-dione (158788-56-8) + C11H20N2O8 → C20H28N2O10

Guidance literature:

With sodium hydrogencarbonate; In water; N,N-dimethyl-formamide; at 0 ℃; for 2h;

upstream raw materials:

1-hydroxy-pyrrolidine-2,5-dione

3,5-dimethyl-4-hydroxybenzoic acid

Downstream raw materials:

2',6'-dimethyl-4'-N-succinimidyloxycarbonylphenyl acridine-9-carboxylate

Refernces