2-{(E)-[(4-Methylphenyl)methylidene]amino}benzene-1-thiol

Base Information

• Chemical Name: 2-{(E)-[(4-Methylphenyl)methylidene]amino}benzene-1-thiol
• CAS No.: 159022-10-3
• Molecular Formula: C14H13NS
• Molecular Weight: 227.33
• DSSTox Substance ID: DTXSID60572758
• Nikkaji Number: J3.144.154D,J2.638.975E
• Mol file: 159022-10-3.mol

Synonyms:159022-10-3;DTXSID60572758;2-{(E)-[(4-Methylphenyl)methylidene]amino}benzene-1-thiol

Chemical Property of 2-{(E)-[(4-Methylphenyl)methylidene]amino}benzene-1-thiol

Chemical Property:

• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 227.07687059
• Heavy Atom Count: 16
• Complexity: 231

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C=NC2=CC=CC=C2S

Technology Process of 2-{(E)-[(4-Methylphenyl)methylidene]amino}benzene-1-thiol

There total 1 articles about 2-{(E)-[(4-Methylphenyl)methylidene]amino}benzene-1-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-methyl-benzaldehyde (104-87-0) + 2-amino-benzenethiol (137-07-5) → N-(4-methylbenzylidene)-o-amino-thiophenol (159022-10-3)

Guidance literature:

In ethanol; Cooling with ice;

DOI:10.1080/15533174.2010.522646

Reference yield: 92.0%

N-(4-methylbenzylidene)-o-amino-thiophenol (159022-10-3) → 2-(4-methylphenyl)-1,3-benzothiazole (16112-21-3)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 20 ℃;

DOI:10.1055/s-0029-1217136

Reference yield: 87.0%

N-(4-methylbenzylidene)-o-amino-thiophenol (159022-10-3) → bis-(2-(4-methylbenzalamino)phenyl)disulfide

Guidance literature:

With 10 wtpercent cubic Ag₂O nanoparticle incorporated mesoporous silica; air; In water; for 5h; chemoselective reaction; Reflux; Green chemistry;

DOI:10.1039/c4ra14802a

upstream raw materials:

4-methyl-benzaldehyde

2-amino-benzenethiol

Downstream raw materials:

2-(4-methylphenyl)-1,3-benzothiazole

2-p-tolyl-2,3-dihydro-benzothiazole