Methyl 4-[2-(2-hydroxyethoxy)ethoxy]benzoate

Base Information

Chemical Name:Methyl 4-[2-(2-hydroxyethoxy)ethoxy]benzoate
CAS No.:159550-14-8
Molecular Formula:C12H16O5
Molecular Weight:240.256
Hs Code.:
DSSTox Substance ID:DTXSID101256182
Mol file:159550-14-8.mol

Synonyms:159550-14-8;methyl 4-[2-(2-hydroxyethoxy)ethoxy]benzoate;SCHEMBL7196751;DTXSID101256182;AKOS013499179

Suppliers and Price of Methyl 4-[2-(2-hydroxyethoxy)ethoxy]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl 4-[2-(2-hydroxyethoxy)ethoxy]benzoate

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:240.09977361
Heavy Atom Count:17
Complexity:211

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC=C(C=C1)OCCOCCO

Technology Process of Methyl 4-[2-(2-hydroxyethoxy)ethoxy]benzoate

There total 3 articles about Methyl 4-[2-(2-hydroxyethoxy)ethoxy]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 628-89-7
2-(2-Chloroethoxy)ethanol

: 99-76-3,156291-94-0
methyl 4-hydroxylbenzoate

: 159550-14-8
methyl 4-[2-(2-hydroxyethoxy)ethoxy]-benzoate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; Reflux;
DOI:10.1021/jm101323b

Reference yield: 80.0%

: 159550-14-8
methyl 4-[2-(2-hydroxyethoxy)ethoxy]-benzoate

Guidance literature:: With N-Methyldicyclohexylamine; C₄₆H₆₇BN₂; nickel dibromide; In N,N-dimethyl-formamide; at 40 ℃; for 12h;

Reference yield:

: 99-96-7
4-hydroxy-benzoic acid

: 159550-14-8
methyl 4-[2-(2-hydroxyethoxy)ethoxy]-benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / Reflux

2: potassium carbonate / N,N-dimethyl-formamide / Reflux

With sulfuric acid; potassium carbonate; In N,N-dimethyl-formamide; 1: Fischer esterification;
DOI:10.1021/jm101323b