(3-Chlorocyclobutyl)methanol

Base Information

Chemical Name:(3-Chlorocyclobutyl)methanol
CAS No.:15963-47-0
Molecular Formula:C5H9ClO
Molecular Weight:120.579
Hs Code.:2906199090
DSSTox Substance ID:DTXSID30550326
Mol file:15963-47-0.mol

Synonyms:(3-Chlorocyclobutyl)methanol;15963-47-0;3-Chlorocyclobutanemethanol;Cyclobutanemethanol, 3-chloro-;MFCD16659929;SCHEMBL9366105;DTXSID30550326;YETIMGFGOCVNQL-UHFFFAOYSA-N;1-Chloro-3-hydroxymethylcyclobutane;AKOS016005537;PB34804;DS-18304;SY097865;CS-0044084;EN300-315363;A846254

Suppliers and Price of (3-Chlorocyclobutyl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3-Chlorocyclobutyl)methanol
100mg
$ 75.00

SynQuest Laboratories
(3-Chlorocyclobutyl)methanol
1 g
$ 776.00

SynQuest Laboratories
(3-Chlorocyclobutyl)methanol
250 mg
$ 368.00

Matrix Scientific
(3-Chlorocyclobutyl)methanol 97.0%
1g
$ 594.00

Crysdot
(3-Chlorocyclobutyl)methanol 95+%
1g
$ 180.00

Chemenu
(3-chlorocyclobutyl)methanol 95%
10g
$ 699.00

Apolloscientific
(3-Chlorocyclobutyl)methanol
1g
$ 704.00

American Custom Chemicals Corporation
(3-CHLOROCYCLOBUTYL)METHANOL 95.00%
5MG
$ 504.77

AK Scientific
(3-Chlorocyclobutyl)methanol
5g
$ 859.00

AK Scientific
(3-Chlorocyclobutyl)methanol
1g
$ 369.00

Total 18 raw suppliers

Chemical Property of (3-Chlorocyclobutyl)methanol

Chemical Property:

Vapor Pressure:0.12mmHg at 25°C
Boiling Point:193.9oC at 760 mmHg
PKA:15.05±0.10(Predicted)
Flash Point:71oC
PSA：20.23000
Density:1.17g/cm3
LogP:0.99610
Storage Temp.:2-8°C
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:120.0341926
Heavy Atom Count:7
Complexity:59.1

Purity/Quality:

97% ^*data from raw suppliers

(3-Chlorocyclobutyl)methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CC1Cl)CO
Uses (3-Chlorocyclobutyl)methanol is used as a reactant in the synthesis of fluoromethylenedimethylprostacyclins as potent anti-anginal agents.

Technology Process of (3-Chlorocyclobutyl)methanol

There total 8 articles about (3-Chlorocyclobutyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 35207-71-7
3-chlorocyclobutane-1-carboxylic acid

: 15963-47-0
3-chlorocyclobutanemethanol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at -50 ℃; for 14h; to room temperature;
DOI:10.1016/0040-4020(95)00468-N

Reference yield: 54.0%

: 15963-46-9,177498-41-8,177498-42-9
3-chlorocyclobutanecarboxylic acid methyl ester

: 15963-47-0
3-chlorocyclobutanemethanol

Guidance literature:: With lithium aluminium tetrahydride;
DOI:10.1021/jo00392a047

Reference yield:

: 5445-51-2
cyclobutane-1,1'-dicarboxylic acid

: 15963-47-0
3-chlorocyclobutanemethanol

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) SOCl₂, (PhCO₂)2 / 1.) C₆H₆, 2.) 200 deg C

2: SOCl₂

3: LiAlH₄ / diethyl ether; tetrahydrofuran / -20 °C

With lithium aluminium tetrahydride; thionyl chloride; dibenzoyl peroxide; In tetrahydrofuran; diethyl ether;
DOI:10.1002/ijch.199600033