Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 8-chloro-

Base Information

Chemical Name:Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 8-chloro-
CAS No.:160657-04-5
Molecular Formula:C11H7ClN2O
Molecular Weight:218.642
Hs Code.:
DSSTox Substance ID:DTXSID40443750
Wikidata:Q82261692

Synonyms:160657-04-5;Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 8-chloro-;8-Chloropyrrolo[1,2-a]quinoxalin-4(5H)-one;8-CHLORO-5H-PYRROLO[1,2-A]QUINOXALIN-4-ONE;SCHEMBL2429766;DTXSID40443750;ODZHADFIGDDGQZ-UHFFFAOYSA-N

Suppliers and Price of Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 8-chloro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 8-chloro-

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:218.0246905
Heavy Atom Count:15
Complexity:284

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN2C(=C1)C(=O)NC3=C2C=C(C=C3)Cl

Technology Process of Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 8-chloro-

There total 3 articles about Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 8-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 1315282-52-0
N-(2-bromo-4-chlorophenyl)-1H-pyrrole-2-carboxamide

: 1H-pyrrole-2-carboxylic acid (2-bromophenyl)amide

: 160657-04-5
8-chloropyrrolo[1,2-a]quinoxalin-4(5H)-one

Guidance literature:: With copper(l) iodide; sodium hydride; L-proline; In N,N-dimethyl-formamide; at 140 - 160 ℃; for 0.416667h; Inert atmosphere; Microwave irradiation;
DOI:10.1039/c1ob05269a

Reference yield:

: 5427-82-7
1H-pyrrole-2-carbonyl chloride

: 1H-pyrrole-2-carboxylic acid (2-bromophenyl)amide

: 160657-04-5
8-chloropyrrolo[1,2-a]quinoxalin-4(5H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 20 °C / Cooling with ice; Inert atmosphere

2: copper(l) iodide; sodium hydride; L-proline / N,N-dimethyl-formamide / 0.42 h / 140 - 160 °C / Inert atmosphere; Microwave irradiation

With copper(l) iodide; sodium hydride; L-proline; In dichloromethane; N,N-dimethyl-formamide; 2: Ullmann-type reaction;
DOI:10.1039/c1ob05269a

Reference yield:

: 634-97-9
pyrrole-2-carboxyl acid

: 1H-pyrrole-2-carboxylic acid (2-bromophenyl)amide

: 160657-04-5
8-chloropyrrolo[1,2-a]quinoxalin-4(5H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl dichloride / 1 h / 50 °C / Inert atmosphere

2: dichloromethane / 20 °C / Cooling with ice; Inert atmosphere

3: copper(l) iodide; sodium hydride; L-proline / N,N-dimethyl-formamide / 0.42 h / 140 - 160 °C / Inert atmosphere; Microwave irradiation

With copper(l) iodide; oxalyl dichloride; sodium hydride; L-proline; In dichloromethane; N,N-dimethyl-formamide; 3: Ullmann-type reaction;
DOI:10.1039/c1ob05269a